Publications by authors named "Mannion C"

Article Synopsis
  • Postgraduate opportunities for oral and maxillofacial surgery (OMFS) vary greatly between medical foundation year (FY) doctors and dental core trainees (DCTs), with 2023-24 data showing more than 11 times as many posts for DCTs.
  • The study utilizes data from UK foundation schools and Health Education England to analyze this disparity, emphasizing the significance of interprofessional education (IPE) and collaboration (IPC).
  • The aim is to raise awareness of the unique learning environment in OMFS and encourage further research into the impact of different professional backgrounds on team dynamics and patient care.
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Background: Bladder duplication is a rare congenital lower urinary tract anomaly disease characterized by the presence of two bladders, possibly with duplication of the urethra. This disease is rarely reported in cats. The clinical symptoms are commonly occult, with increased difficulty in making a definitive diagnosis, especially if there is no obvious urethral duplication.

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Among patients with triple-negative breast cancer (TNBC), several studies have suggested that deregulated microRNA (miRNA) expression may be associated with a more aggressive phenotype. Although tumor molecular signatures may be race- and/or ethnicity-specific, there is limited information on the molecular profiles in women with TNBC of Hispanic and Latin American ancestry. We simultaneously profiled TNBC biopsies for the genome-wide copy number and miRNA global expression from 28 Latina women and identified a panel of 28 miRNAs associated with copy number alterations (CNAs).

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In 2017, the hibiscus bud weevil (HBW), Linell (Coleoptera: Curculionidae), was found outside of its native range of Mexico and Texas, infesting hibiscus plants in Florida. Therefore, we selected 21 different insecticide and horticultural oil products to evaluate their effects on the reproductive rate, feeding, and oviposition behavior of the HBW. In laboratory experiments, significant mortality was observed in adult weevils exposed to diflubenzuron-treated hibiscus leaves and buds, and hibiscus buds treated with diflubenzuron contained the fewest number of eggs and feeding/oviposition holes.

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The COVID-19 pandemic and related social restrictions disrupted family routines affecting millions of youths and their caregivers worldwide. This study explored the relationship between caregivers' anxiety and their children's emotional states 1 year after COVID-19, as well as differences between caregivers' perceptions of their children's emotional states and reality. Sixty-eight caregiver-child pairs completed an online survey between March 31 and May 31, 2021.

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Breast cancer development and progression are believed to be a sequential process, from normal to hyperplastic, to , and to invasive and metastatic stages. Given that over 90% of cancer deaths are caused by invasive and metastatic lesions, countless factors and multiple theories have been proposed as the triggering factor for the cascade of actions of cancer invasion. However, those factors and theories are largely based on the studies of cell lines or animal models.

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Over the past two decades, the global efforts for the early detection and intervention of prostate cancer seem to have made significant progresses in the basic researches, but the clinic outcomes have been disappointing: (1) prostate cancer is still the most common non-cutaneous cancer in Europe in men, (2) the age-standardized prostate cancer rate has increased in nearly all Asian and African countries, (3) the proportion of advanced cancers at the diagnosis has increased to 8.2% from 3.9% in the USA, (4) the worldwide use of PSA testing and digital rectal examination have failed to reduce the prostate cancer mortality, and (5) there is still no effective preventive method to significantly reduce the development, invasion, and metastasis of prostate cancer… Together, these facts strongly suggest that the global efforts during the past appear to be not in a correlated target with markedly inconsistent basic research and clinic outcomes.

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Objective: We investigated using "pulsatile vessels at the posterior bladder wall" as a novel sonographic marker to demonstrate the severity of placenta accreta spectrum (PAS).

Methods: This observational case-control study of 30 pregnant women was performed at Hackensack Meridian Health's Center for Abnormal Placentation in 2020. The case group was made up of women with historically described sonographic signs of PAS and was compared against two control groups: (1) women with uncomplicated placenta previa and (2) women with no evidence of placenta previa sonographically.

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Originating in northeastern Mexico and southern Texas, the hibiscus bud weevil (HBW), Linell 1897, was discovered infesting China rose hibiscus ( L.) in south Florida in May 2017. Although the biologies of the congeneric boll weevil, Boheman 1843, and pepper weevil, Cano 1894 are well documented, no data are available regarding the biology of HBW.

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Research using nonhuman primate models for human disease frequently requires behavioral observational techniques to quantify functional outcomes. The ability to assess reaching and grasping patterns is of particular interest in clinical conditions that affect the motor system (e.g.

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Introduction: The SARS-CoV-2 pandemic forced many governments to impose nation-wide lockdowns. Government legislation forced limited travel on the population with restrictions on the normal way of life to limit spread of the SARS-CoV-2 virus. The aim of this study is to explore the effects of lockdown on the presentation of maxillofacial trauma in a level I trauma centre.

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This qualitative study explored the impressions of pregnant Canadian women toward (CFG) snapshot released in January 2019. Semi-structured interviews were conducted with 8 physically active pregnant women. Interviews were digitally recorded, transcribed verbatim, and analyzed using thematic analysis.

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More than 50% of patients with colorectal cancer (CRC) develop liver metastases during the natural course of disease. Surgical resection is currently the most potentially curative method in the treatment of colorectal liver metastases (CRLM). The goal of surgery is to achieve a negative resection margin (RM) of at least 1 mm, which provides the best prognosis for patients.

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Background/aims: Peripatetic teaching originated in the Aristotelian school of ancient Greece and refers to the action of walking, discussion and deep learning. A pilot study was carried out to evaluate the educational impact of peripatetic teaching in clinical medical education. There has been no previous evaluation of this form of teaching within medical education.

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Background: Cyanide is one of the most rapidly acting toxins affecting cattle, with poisoning typically occurring following ingestion of cyanogenic plants. Laurel (Prunus laurocerasus), is one such potentially toxic cyanogenic plant. This case report details fatalities in an Irish herd following the ingestion of laurel and aims to raise awareness of the potential risk that access to laurel hedges poses to farm animals.

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We reviewed five cohorts of dental core trainees over a five-year period in a single unit (2013-2018). We identify specific motivators for undertaking dental core training and common career paths. We suggest how mentorship and educational supervision is an important part of the overall experience.

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Background: The World Health Organization lists vaccine hesitancy as one of 10 threats to global health. The antivaccine movement uses Facebook to promote messages on the alleged dangers and consequences of vaccinating, leading to a reluctance to immunize against preventable communicable diseases.

Objective: We would like to know more about the messages these websites are sharing via social media that can influence readers and consumers.

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COVID-19 is a global pandemic of unprecedented proportions. It has resulted in changes to all aspects of our lives. The impact on medicine has been significant.

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Background: Studies have indicated variability around prevalence estimates of multimorbidity due to poor consensus regarding its definition and measurement. Medication-based measures of morbidity may be valuable resources in the primary-care setting where access to medical data can be limited. We compare the agreement between patient self-reported and medication-based morbidity; and examine potential patient-level predictors of discordance between these two measures of morbidity in an older (≥ 50 years) community-based population.

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Various antibiotics have been used in the treatment of cancers, via their anti-proliferative, pro-apoptotic and anti-epithelial-mesenchymal-transition (EMT) capabilities. However, increasingly studies have indicated that antibiotics may also induce cancer generation by disrupting intestinal microbiota, which further promotes chronic inflammation, alters normal tissue metabolism, leads to genotoxicity and weakens the immune response to bacterial malnutrition, thereby adversely impacting cancer treatment. Despite the advent of high-throughput sequencing technology in recent years, the potential adverse effects of antibiotics on cancer treatments via causing microbial imbalance has been largely ignored.

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Excellence in teaching and learning is fundamental to the provision of quality training for doctors and for this a sound knowledge of the principles of adult learning theory is important. We present an educational course in head and neck trauma skills for emergency medicine (EM) registrars, using the pedagogical principle of active learning. Our aim was to provide trainees with skills in the evaluation and management of hard and soft tissue injuries to the head, neck, and mouth.

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Resilience is the process of 'bouncing back' from stresses in life. High resilience is associated with less anxiety and psychological distress, and is therefore an important trait for health professionals. We know of no work to date on the resilience of dental core trainees (DCT) as they make the unique transition from dental practice to a hospital-based setting.

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This qualitative grounded theory pilot study investigated the concerns and coping mechanisms of mothers of very low-birth-weight (VLBW; <1500 g) infants following discharge from the neonatal intensive care unit in Alberta, Canada. In-depth, semistructured, face-to-face, audio-recorded interviews were conducted with women of VLBW infants. Interviews lasting 75 to 90 minutes were transcribed verbatim and coded using grounded theory methodology.

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Medication-related osteonecrosis of the jaws (MRONJ) is a rare complication of bisphosphonates, or antiresorptive or antiangiogenic medication. Treatment is difficult as the bone has a poor capacity for healing, and further progression after surgery can occur. Quality of life (QoL) in patients with MRONJ has not been well documented.

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