Could cathodal transcranial direct current stimulation modulate the power spectral density of alpha-band in migrainous occipital lobe?

Objective: To identify the correlation between cathodal transcranial direct current stimulation (tDCS) and the power spectral density (PSD) of alpha-band on the occipital lobe of migraineurs.

Methods: Firstly, a cross-sectional study was performed to compare the PSD of alpha-band in the occipital cortex of 25 migraineurs versus 10 healthy volunteers in resting state and during repetitive light stimuli (RLS). Secondly, the patients participated in 12 sessions of cathodal (n = 11) or sham tDCS (n = 10) over the primary visual cortex (V1) to investigate the alpha-band PSD.