Oxidative biotransformation of stemofoline alkaloids.

Biotransformations of stemofoline (), (2')-hydroxystemofoline (), (11)-1',2'-didehydrostemofoline () and stemocurtisine () were studied through fermentation with TISTR 3370. Three new stemofoline derivatives; 6 -hydroxystemofoline (), (2', 6 )-dihydroxystemofoline () and (11,6)-1',2'-didehydro-6-hydroxystemofoline (), together with the known compound 1',2'-didehydrostemofoline--oxide (), were produced by C-hydroxylation and N-oxidation reactions. Stemocurtisine was not biotransformed under these conditions.

Cytotoxic and larvicidal activities of alkaloids from the aerial parts and roots of Hook.f.

A new alkaloid glycoside derivative, 6-hydroxy-5,6-seco-stemocurtisinoside (), was isolated from the ethanolic extract of the aerial parts of Hook.f., together with stemocurtisine (), (11)-1',2'-didehydrostemofoline () and 6-hydroxy-5,6-seco-stemocurtisine ().

Synthesis of Hydroxyapatite with Antibacterial Properties Using a Microwave-Assisted Combustion Method.

The prevention of implant-associated infections has been increasing clinically in orthopedic surgery. Hydroxyapatite with antibacterial properties was synthesized using a microwave-assisted combustion method. High crystallinity at low temperature can be achieved using this method.