Cases of sickle cell disease with dengue during pregnancy have rarely been reported. Sickle cell disorder is one of the most commonly inherited genetic disorders, especially in certain regions of India. Sickle cell disease, especially in pregnancy, has varying clinical severity, which may potentially lead to serious complications, negatively affecting the maternal and fetal outcomes.
View Article and Find Full Text PDFEmbryo transfer is a pivotal procedure in assisted reproductive technologies (ART). Yet, the success of this process hinges on multiple factors, with endometrial receptivity playing a critical role in determining the likelihood of successful implantation. The endometrial receptivity array (ERA) is an advanced diagnostic tool designed to personalize embryo transfer timing by assessing the endometrium's receptivity.
View Article and Find Full Text PDFUterine fibroids, or leiomyomas, are common benign tumors of the uterus, generally asymptomatic but potentially causing severe symptoms and complications in some cases, as demonstrated in this report. This case presents significant management challenges due to the fibroids' size, number, and location, including an unusual complication involving adhesion to the ileum. A 40-year-old female with a history of P2L1D1 and no significant comorbidities presented with three months of progressive abdominal pain and a rapidly enlarging mass resembling a 30- to 32-week gravid uterus and heavy menstrual bleeding.
View Article and Find Full Text PDFThe most frequent and harmful side effect of childbirth is obstetric haemorrhage. Postpartum haemorrhage (PPH) remains the primary cause of maternal mortality worldwide. Most PPH-related deaths take place in the first 24 hours of life.
View Article and Find Full Text PDFPyometra is a very uncommon condition in postmenopausal women that rarely improves with standard antibiotic treatments. It is usually overlooked as the patient presents with vague symptoms. Our case presented a postmenopausal woman with sepsis due to a huge pyometra.
View Article and Find Full Text PDFEndometriosis is a prevalent yet often underdiagnosed condition characterized by the presence of endometrial-like tissue outside the uterus, leading to significant morbidity and impaired quality of life. A timely and accurate diagnosis of endometriosis is essential for effective management and improved patient outcomes. This review provides a comprehensive overview of the current diagnostic landscape of endometriosis, including clinical evaluation, imaging modalities, biomarkers, and laparoscopy.
View Article and Find Full Text PDFGallstone-related complications during pregnancy, though relatively rare, present significant challenges necessitating careful clinical management. Among these complications, the simultaneous occurrence of acute cholecystitis and choledocholithiasis poses a unique dual challenge, especially considering the physiological changes and fetal considerations associated with pregnancy. This case report presents the management of a 27-year-old pregnant woman with acute cholecystitis and choledocholithiasis at 32 weeks of gestation.
View Article and Find Full Text PDFThe journey of addressing fertility challenges, especially in the context of fallopian tubal issues, has witnessed remarkable advancements. This comprehensive review delves into microsurgery for fallopian tubal re-canalization within the era of in vitro fertilization (IVF). The review begins by providing the historical backdrop, tracing the evolution of this surgical technique, and highlighting the transformative impact of microsurgical methods and instrumentation on its precision and outcomes.
View Article and Find Full Text PDFOvarian germ cell tumors constitute a rare and intricate spectrum of neoplasms characterized by diverse histological subtypes. This comprehensive review elucidates the classification, diagnosis, treatment, prognosis, and unique challenges associated with these tumors. The classification is rooted in histological attributes, with principal subtypes encompassing dysgerminoma, immature teratoma, yolk sac tumor (endodermal sinus tumor), choriocarcinoma, and mixed germ cell tumors.
View Article and Find Full Text PDFUterine leiomyomas are benign uterine tumors arising from the smooth muscle cells of the myometrium. Most of them are asymptomatic, and rarely do they present with symptoms like infertility, abdominal distension, and acute abdomen. According to experts, the most common cause of acute abdomen is torsion of a pedunculated subserosal leiomyoma, which is an extremely rare and life-threatening surgical emergency.
View Article and Find Full Text PDFIn recent decades, small organic compounds having absorption and fluorescence emission in the second near-infrared (NIR-II, 1000-1700 nm) bio-window have attracted a lot of interest. Fluorescence bioimaging may be used by researchers and surgeons to genomically focus an array of biological areas and functions. The near-infrared-II (NIR-II) dye which has fluorescent imaging, bypasses the visible imaging striking barrier, making it a valuable tool for cancer early detection and very sensitive tumor resection.
View Article and Find Full Text PDFBackgrounds A significant contributor to newborn morbidity and mortality is preterm birth. Several techniques have been employed to identify patients at risk of premature labour. However, these predictors are not always effective because of their multifactorial aetiology.
View Article and Find Full Text PDFBackground One of the most prevalent medical issues observed during pregnancy is hypertension. Hypertensive disorders of pregnancy (HDP) and their consequences affect around 5-10% of all pregnancies globally. Preeclampsia is caused by endothelial dysfunction, which causes widespread endothelial leakage and contributes to potentially fatal consequences, such as eclampsia, placental abruption, disseminated intravascular coagulation (DIC), severe renal failure, pulmonary edema, and hepatocellular necrosis.
View Article and Find Full Text PDFSubclinical hypothyroidism is characterized by raised thyroid-stimulating hormone levels in the presence of normal free thyroxine levels. When free thyroxine levels are normal and subclinical hypothyroidism is present, thyroid-stimulating hormone levels are elevated. The impact of subclinical hypothyroidism on the cardiovascular system has recently garnered attention because it is known that thyroid hormones impact the heart and its vasculature.
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