Brugada Syndrome: The Role of Risk Stratification in Selecting Patients for Implantable Cardioverter-defibrillator Placement.

Brugada syndrome (BS) is an inherited cardiac ion channelopathy that is a rare, but treatable, cause of sudden cardiac death (SCD). There are many studies that explore the management of symptomatic BS, but few trials have been conducted regarding management of asymptomatic Brugada patients. Asymptomatic BS patients are shown to be at increased risk (0.

Prevention of Stress-Provoked Endothelial Injury by Values Affirmation: a Proof of Principle Study.

Background: Few studies have tested whether cellular processes directly associated with cardiovascular disease risk can be influenced by a psychological inoculation.

Purpose: This study investigated whether values affirmation, a psychological procedure designed to reduce stress and threat perception, would prevent endothelial injury to social evaluative threat (SET).

Methods: Participants (N=32) were randomized to SET, SET with values affirmation, or Control.

Are there consequences of labeling patients with prehypertension? An experimental study of effects on blood pressure and quality of life.

Objective: The prehypertension classification was introduced to facilitate prevention efforts among patients at increased risk for hypertension. Although patients who have been told that they have hypertension report worse outcomes than unaware hypertensives, little is known about whether or not prehypertension labeling has negative effects. We evaluated the effects of labeling individuals with prehypertension on blood pressure and health-related quality of life three months later.

Relation between leukocyte telomere length and incident coronary heart disease events (from the 1995 Canadian Nova Scotia Health Survey).

Leukocyte telomere length has been proposed as a biomarker of cellular aging and atherosclerosis. The aim of this study was to determine whether leukocyte telomere length is independently associated with incident coronary heart disease (CHD) in the general population. Telomere length was measured using a polymerase chain reaction method for participants enrolled in the 1995 Nova Scotia Health Survey (NSHS95; n = 1,917).