Validation of Kidney Disease Quality of Life Short Form 36 (KDQOL-SF™) in Malayalam among Patients Undergoing Haemodialysis in South Kerala.

Introduction: Hemodialysis is the most common mode of therapy worldwide for chronic kidney disease (CKD) and is used as a life-sustaining therapy for most of the patients. Studies proved that dialysis affects the Quality of life (QOL) of patients. Health-related quality of life has been increasingly recognized as an important medical outcome in patients with CKD.

Public perception and preparedness for the pandemic COVID 19: A Health Belief Model approach.

Background: Coronavirus disease 2019(COVID-19) pandemic is recognized as a major threat to human health in 2020. As the disease is new and spreading quickly, the scientific community is reporting new information daily to address this issue. The public is well informed and is ready to adopt the protective and preventive measures suggested by the authorities.

Urinary bladder cancer risk among motor vehicle drivers: a meta-analysis of the evidence, 1977-2008.

Background: The aim of the study was to summarize bladder cancer risk in motor vehicle drivers and railroad workers using meta-analysis techniques.

Methods: We retrieved all published results (3 cohort studies and 27 case-control studies) during 1977-2008. We assessed the heterogeneity of the results assuming a fixed-effect model.

Magnesium deficiency augments myocardial response to reactive oxygen species.

Magnesium (Mg) deficiency and oxidative stress are independently implicated in the etiopathogenesis of various cardiovascular disorders. This study was undertaken to examine the hypothesis that Mg deficiency augments the myocardial response to oxidative stress. Electrically stimulated rat papillary muscle was used for recording the contractile variation.

Reduction of perifusate magnesium alters inotropic response of papillary muscle to ion channel modulators.

Magnesium has a significant role in the regulation of ion transport. Marginal deficiency of Mg can therefore affect myocardial excitability and contractility. This study was taken up with the objective of examining the inotropic response of the myocardium to variation in extracellular [Mg]o and identifying the ion channels and pumps mediating the inotropic changes.

Negative inotropic response to cerium in ventricular papillary muscle is mediated by reactive oxygen species.

This study was performed with the objective of assessing the mechanical response of the myocardium to different levels of cerium and delineation of the mechanism underlying the mediation of the functional changes. Rat ventricular papillary muscle was used as the experimental model. Isolated papillary muscles were exposed to different concentrations of CeCl3 and the force of contraction was measured using a force transducer.