Publications by authors named "Manju Janardhanan"

Article Synopsis
  • The study focuses on evaluating the cumulative clinical benefits and costs of various biologics for treating moderate to severe psoriasis over a 16-week period, as opposed to simply assessing their effects at a single point in time.
  • It employs a network meta-analysis to compare biologics like ixekizumab and adalimumab using the Psoriasis Area and Severity Index (PASI) to quantify treatment effectiveness and cost-effectiveness.
  • Results indicate that ixekizumab showed the highest cumulative benefits, achieving significant PASI responses, particularly with a notable percentage of patients reaching clear skin scores within the treatment period.
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Adverse reactions and toxicity inevitably accompany all treatment courses for drug-resistant TB. Our case underscores the importance of awareness regarding neuropsychiatric adverse reactions due to MDR-TB therapy and reversible nature of it. Cycloserine induced psychosis is most life threatening complication and sometimes could be fatal.

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The most important and unique adverse effect of abacavir (ABC) is fatal hypersensitivity reaction (HSR). The objective of this report is to describe a case of ABC induced HSR that occurred in an Indian HIV patient during treatment. Although this adverse effect is not uncommon, it is perhaps underreported or has never been reported so far in an Indian case scenario.

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