Deciphering gene specific molecular characterization and partial gene sequence for combined resistance to tomato leaf curl virus (ToLCV) (Ty-1, Ty-2 and Ty-3), fusarium wilt (I-2) and root- knot nematode (Mi-1) in selected fresh market breeding line of tomato (Solanum lycopersicom L.).

Background: Tomato (Solanum lycopersicum L.) is a widely cultivated crop in tropical regions, but its production is often hampered by significant losses attributed to diseases like tomato leaf curl virus (ToLCV), fusarium wilt and root-knot nematode.

Methods And Results: This study employed an integrated approach utilizing both co-dominant and dominant SCAR markers, selected for specific resistance genes (ToLCV-Ty-1, Ty-2, Ty-2, Fusarium wilt (Race-2)-I-2, and Root-knot nematode-Mi-1.

Retinal Vessel Plexus Differentiation Based on OCT Angiography Using Deep Learning.

Purpose: Although structural OCT is traditionally used to differentiate the vascular plexus layers in OCT angiography (OCTA), the vascular plexuses do not always obey the retinal laminations. We sought to segment the superficial, deep, and avascular plexuses from OCTA images using deep learning without structural OCT image input or segmentation boundaries.

Design: Cross-sectional study.

Time-to-Positivity for Candida in Bloodstream Infections: Prognostic Implications for Mortality.

Background -associated catheter-related bloodstream infections (CRBSIs) present a significant challenge in clinical settings, particularly among patients with central venous catheters (CVCs). Time-to-positivity (TTP) of blood cultures, an indicator of fungal load, may provide insights into infection prognosis and severity. This study evaluates the role of TTP in -associated bloodstream infections and its impact on patient outcomes.

ETDRS grading with CLARUS ultra-widefield images shows agreement with 7-fields colour fundus photography.

Background: To analyse and compare the grading of diabetic retinopathy (DR) severity level using standard 35° ETDRS 7-fields photography and CLARUS™ 500 ultra-widefield imaging system.

Methods: A cross-sectional analysis of retinal images of patients with type 2 diabetes (n = 160 eyes) was performed for this study. All patients underwent 7-fields colour fundus photography (CFP) at 35° on a standard Topcon TRC-50DX camera, and ultra-widefield (UWF) imaging at 200° on a CLARUS™ 500 (ZEISS, Dublin, CA, USA) by an automatic montage of two 133° images (nasal and temporal).

Antibacterial Activity of (Rosella) Using Methanolic Extract.

L. (Rosella) has a long history of use in food preparation, herbal remedies, hot and cold beverages, food industry flavoring, and herbal drinks. More than 300 species of are grown all over the world.

Antimicrobial Activity and Biological Compatibility Study of Methanolic Crude Extract of (Flower).

is a little flowering tree or shrub that is indigenous to India and Sri Lanka. It is also known by the names Tanner's Cassia and Avarampoo. It is a member of the Fabaceae family and is popular for its therapeutic and beautifying effects.

Antimicrobial Activity of Crude Metabolites of using Methanol Extract against the Clinical Pathogens.

Background: The , also known as grapevine, is one of the most widely grown fruit crops in the world and is renowned for producing wine and grapes. Other than their importance in gastronomy and ecology, certain sections of the plant have shown promising bioactive qualities. The numerous phytochemicals in this plant, including flavonoids, stilbenes, and phenolic acids, are what gives its antibacterial and antifungal properties though the antimicrobial properties of seed extract have to be studied, however in this present study we focus on screening and its biological compatibility of seed extracts of .

Deep learning-based algorithm for the detection of idiopathic full thickness macular holes in spectral domain optical coherence tomography.

Background: Automated identification of spectral domain optical coherence tomography (SD-OCT) features can improve retina clinic workflow efficiency as they are able to detect pathologic findings. The purpose of this study was to test a deep learning (DL)-based algorithm for the identification of Idiopathic Full Thickness Macular Hole (IFTMH) features and stages of severity in SD-OCT B-scans.

Methods: In this cross-sectional study, subjects solely diagnosed with either IFTMH or Posterior Vitreous Detachment (PVD) were identified excluding secondary causes of macular holes, any concurrent maculopathies, or incomplete records.

Mercury speciation in selenium enriched wheat plants hydroponically exposed to mercury pollution.

Mercury (Hg) pollution in agricultural soils and its potential pathway to the human food chain can pose a serious health concern. Understanding the pathway of Hg in plants and how the speciation may change upon interaction with other elements used for biofortification can be critical to assess the real implications for the final plant-based product. In that respect, selenium (Se) biofortification of crops grown in Se-poor soil regions is becoming a common practice to overcome Se deficient diets.

Liquid resistivity of pharmaceutical propellants using novel resistivity cell.

Metered-dose inhalers employ propellants to produce pharmaceutical aerosols for treating respiratory conditions like asthma. In the liquid phase, the DC volume resistivity of pharmaceutical propellants, including R134a, R152a, and R227ea, was studied at saturation pressures and room temperature (not vapour phase). These measurements are essential for industries like refrigerants.

Exogenous delivery of dsRNA for management of mungbean yellow mosaic virus on blackgram.

Exogenous application of dsRNA molecules targeting MYMV genes offers a promising approach to effectively mitigate yellow mosaic disease in blackgram, demonstrating potential for sustainable plant viral disease management. The exogenous application of double-stranded RNA (dsRNA) molecules to control plant viral diseases is gaining traction due to its advantages over conventional methods, such as target specificity, non-polluting nature, and absence of residue formation. Furthermore, this approach does not involve genome modification.

Facile Synthesis of Benzimidazoles via Oxidative Cyclization of Acyclic Monoterpene Aldehyde with Diamines: Studies on Antimicrobial and in Vivo Evaluation of Zebrafish.

Citral (1a), a bioactive component of Cymbopogon citratus (lemongrass) could be isolated and semi-synthetic analogs synthesized with improved therapeutic properties. Herein we first report describes citral (1a) as a primary material for the synthesis of benzimidazole derivatives between various o-phenylenediamines (2a-l) in the presence of Diisopropylethylamine (DIPEA) as a commercially available environmentally benign base, ethanol as a green solvent and the yield of all benzimidazole derivatives (3a-l) was between 68-76 %; The semi-synthetically prepared benzimidazole derivatives (3a-l) were assessed for their anti-bacterial and anti-fungal properties. The benzimidazole compounds (3a-b, and 3g-j) exhibit good anti-microbial activity.

Multi-location evaluation of mungbean ( L.) in Indian climates: Ecophenological dynamics, yield relation, and characterization of locations.

Crop yield varies considerably within agroecology depending on the genetic potential of crop cultivars and various edaphic and climatic variables. Understanding site-specific changes in crop yield and genotype × environment interaction are crucial and needs exceptional consideration in strategic breeding programs. Further, genotypic response to diverse agro-ecologies offers identification of strategic locations for evaluating traits of interest to strengthen and accelerate the national variety release program.

A Deep Learning Model for Automated Segmentation of Geographic Atrophy Imaged Using Swept-Source OCT.

Purpose: To present a deep learning algorithm for segmentation of geographic atrophy (GA) using en face swept-source OCT (SS-OCT) images that is accurate and reproducible for the assessment of GA growth over time.

Design: Retrospective review of images obtained as part of a prospective natural history study.

Subjects: Patients with GA (n = 90), patients with early or intermediate age-related macular degeneration (n = 32), and healthy controls (n = 16).

Molecular epidemiology on seasonal variation of yellow mosaic disease incidence in blackgram (Vigna mungo L. Hepper) with its vector Bemisia tabaci.

The yellow mosaic disease (YMD) of blackgram caused by Mungbean yellow mosaic virus has emerged as a serious threat to grain legume production, especially in Southeastern Asia. Seasonal incidence of YMD with its vector population was assessed in three different agroclimatic zones of Tamil Nadu in India for three consecutive cropping seasons namely, Rabi 2018 (October-December), Summer 2019 (March-May), and Kharif 2019 (June-August) at three different time intervals viz., 20, 40, and 60 days after sowing (DAS).

Role of Bone Scan and MRI in Designing of Customized Prosthesis for Limb Salvage Surgery of Long Bone Tumors: 4 Years of Single Institution Analysis.

The purpose of this study is to evaluate the role of bone scan (BS) and MRI measurement data in designing Custom Made Prosthesis (CMP) in Limb Salvage Surgery (LSS) in orthopedic oncology patients. The study was done on 126 patients, which include 88 males and 38 females. Pre-operative planning including determination of the osteotomy plane and dimension of the prosthesis was performed based on Tc99m MDP bone scan and MR images comparing with the histopathology examination (HPE) values.

Structural differences and adsorption behaviour of alkaline metals doped zinc oxide nanoparticles.

Nanotechnology plays a vital role in all the scientific fields including environmental research due to their surface: volume ratio compared to bulk materials. Recent studies prove their effectiveness as pollutant removal and remediation practices. Zinc oxide (ZnO) nanoparticles a multifunctional material with distinct properties and their doped counterparts were widely being studied in different fields of science.

Advances in Crop Improvement and Delivery Research for Nutritional Quality and Health Benefits of Groundnut ( L.).

Groundnut is an important global food and oil crop that underpins agriculture-dependent livelihood strategies meeting food, nutrition, and income security. Aflatoxins, pose a major challenge to increased competitiveness of groundnut limiting access to lucrative markets and affecting populations that consume it. Other drivers of low competitiveness include allergens and limited shelf life occasioned by low oleic acid profile in the oil.

Steady expression of high oleic acid in peanut bred by marker-assisted backcrossing for fatty acid desaturase mutant alleles and its effect on seed germination along with other seedling traits.

Peanut (Arachis hypogaea L.) is an important nutrient-rich food legume and valued for its good quality cooking oil. The fatty acid content is the major determinant of the quality of the edible oil.

Substituent enhanced fluorescence properties of star α-cyanostilbenes and their application in bioimaging.

A series of star α-cyanostilbenes with D-π-A structures comprising triphenylamine as the donor, the cyanovinyl group as the acceptor and different substituents on the terminal phenyl rings were synthesized and characterized. The influence of the substituents on the photophysical, electrochemical and thermal properties of the star molecules was investigated in detail. A strongly electron withdrawing nitro substituent on the phenyl ring (NTBTNPA) increased the absorption and emission maxima, the Stokes shift, and the difference between the ground and excited state dipole moments and decreased the fluorescence quantum yield, fluorescence lifetime and band gap energy between the highest occupied molecular orbital (HOMO) and the lowest unoccupied molecular orbital (LUMO).

Growth optimization, free radical scavenging and antibacterial potential of Chlorella sp. SRD3 extracts against clinical isolates.

Aim: The aim of present work was to explore the potential of Chlorella sp. SRD3 extracts for antioxidant and antibacterial activity along with the evaluation of minimum inhibitory concentration (MIC) and haemolytic activity to detect RBC cell damage.

Methods And Results: Screening and isolation of microalgae was performed using bold basal medium under normal illuminance (at 27°C) and microscopic observation.