Globe rupture with aphakia, aniridia, secondary glaucoma and late corneal decompensation: A multi-staged approach to management.

Severe blunt ocular trauma may result in immediate and delayed complications requiring appropriate management algorithms. We hereby report a case of globe rupture, aphakia, traumatic aniridia, and secondary glaucoma in a 33-year-old male following road traffic accident. He was treated initially by primary repair followed by novel combined approach of aniridia IOL with Ahmed glaucoma valve implantation.

A deep dive into the latest European Glaucoma Society and Asia-Pacific Glaucoma Society guidelines and their relevance to India.

Glaucoma is the second leading cause of blindness in India. Despite advances in diagnosing and managing glaucoma, there is a lack of India-specific clinical guidelines on glaucoma. Ophthalmologists often refer to the European Glaucoma Society (EGS) and Asia-Pacific Glaucoma Society (APGS) guidelines.

Visual Field Plots: A Comparison Study Between Standard Automated Perimetry and Eye Movement Perimetry.

Unlabelled: PRéCIS:: This eye movement perimetry (EMP) study describes the development of saccadic reaction time (SRT)-based visual field plots, which could effectively display the presence, location, and extent of glaucomatous defects and support clinical decision-making.

Purpose: EMP is capable of discriminating normal from glaucomatous visual field defects on the basis of average delays in SRTs. To classify the presence and extent of age-corrected visual field defects, it is required to create SRT-based probability maps.

Effect of Age, Sex, Stimulus Intensity, and Eccentricity on Saccadic Reaction Time in Eye Movement Perimetry.

Purpose: In eye movement perimetry (EMP), the extent of the visual field is tested by assessing the saccades using an eye tracker. The aim of the present study was to determine the effects of age and sex of the subjects, the eccentricity and intensity of the peripheral stimuli on saccadic reaction time (SRT), and the interaction between these parameters in healthy participants.

Methods: Healthy participants aged between 20 to 70 years underwent a complete ophthalmic examination and an EMP test.

Detection of Proteins Associated with Extracellular Matrix Regulation in the Aqueous Humour of Patients with Primary Glaucoma.

: The protein composition of aqueous humour (AH) has held significant relevance and remains to be the prime sample in the discovery of biomarkers in glaucoma. The purpose of this study is to analyze the AH protein concentrations in primary open angle glaucoma (POAG) and primary angle closure glaucoma (PACG) and further examine the proteome changes compared to cataract control. : AH was collected from 90 POAG, 72 PACG, 78 cataracts (controls) in this study.

Eye Movement Perimetry and Frequency Doubling Perimetry: clinical performance and patient preference during glaucoma screening.

Purpose: To evaluate the screening accuracy of an Eye Movement Perimetry (EMP) in comparison with Frequency Doubling Perimetry (FDP) and to investigate the patient preference and perception towards these visual field screening methods.

Methods: A total of 104 healthy subjects (mean age (SD) of 48 (14) years) and 73 glaucoma patients (mean age (SD) of 52 (13) years) were recruited. All the participants underwent a comprehensive ophthalmic evaluation including the 24-2 SITA standard protocol on the Humphrey Field Analyzer (HFA).

Is prophylactic laser peripheral iridotomy for primary angle closure suspects a risk factor for cataract progression? The Chennai Eye Disease Incidence Study.

Background: To report the risk of cataract progression among primary angle closure suspects (PACS) 6 years after they underwent laser peripheral iridotomy (LPI).

Methods: In the Chennai Eye Disease Incidence Study, 6 years after their baseline evaluation, 4421 subjects were examined again. As part of a detailed evaluation cataract was graded using the Lens Opacities Classification System II; progression was defined as change of cataract by two or more grades or history of cataract surgery in the 6-year period.

Correlation of Aqueous Humor Lysyl Oxidase Activity with TGF-ß Levels and LOXL1 Genotype in Pseudoexfoliation.

Purpose: Pseudoexfoliation (PXF) is a microfibrillopathy involving disordered elastogenesis. Abnormal extracellular matrix (ECM) production underlies the pathophysiology of PXF. The enzyme Lysyl oxidase (LOX) and its isoforms are known to cross-link the elastin and collagen.

Six-year incidence of visually significant age-related cataract: the Chennai eye disease incidence study.

Background: The aim of this study is to report the 6-year incidence of age-related cataract in a population-based study.

Design: The design used is a population-based cohort study.

Participants: A cohort of 2484 phakic subjects, aged 40 years and above at baseline, from a south Indian population was included in the study.

The Prevalence of Pseudoexfoliation and the Long-term Changes in Eyes With Pseudoexfoliation in a South Indian Population.

Purpose: To report the prevalence, long-term changes and associated factors for pseudoexfoliation (PEX) in a population aged 40 years and above from rural and urban south India.

Materials And Methods: At baseline (the Chennai Glaucoma Study), 7774 subjects were examined. After 6 years, as a part of the incidence study, 133 of the 290 subjects diagnosed with PEX at baseline were reexamined for long-term changes.

Six-Year Incidence and Baseline Risk Factors for Pseudoexfoliation in a South Indian Population: The Chennai Eye Disease Incidence Study.

Objective: To estimate the 6-year incidence of pseudoexfoliation and its risk factors in a South Indian population.

Design: Longitudinal population-based study.

Participants: Subjects 40 years of age or older without pseudoexfoliation at baseline.

Six-year incidence of ocular hypertension in a South Indian population: the Chennai eye disease incidence study.

Aims: To report the 6-year incidence and risk factors for ocular hypertension (OHT) in a population-based study in southern India.

Methods: 6 years after baseline evaluation, 56.9% subjects (participants:non-participants, 4421:3353) were re-examined at the base hospital.

Baseline risk factors for incidence of blindness in a South Indian population: the chennai eye disease incidence study.

Purpose: To report the baseline risk factors and causes for incident blindness.

Methods: Six years after the baseline study, 4419 subjects from the cohort underwent a detailed examination at the base hospital. Incident blindness was defined by World Health Organization criteria as visual acuity of less than 6/120 (3/60) and/or a visual field of less than 10° in the better-seeing eye at the 6-year follow-up, provided that the eye had a visual acuity of better than or equal to 6/120 (3/60) and visual field greater than 10° at baseline.

Predictors for incidence of primary open-angle glaucoma in a South Indian population: the Chennai eye disease incidence study.

Objective: To determine the 6-year incidence of primary open-angle glaucoma (POAG) and its associated predictors.

Design: Population-based cohort study.

Participants: A total of 4316 subjects without POAG at baseline who were 40 years of age and older from a south Indian population.

Prospective evaluation of early visual loss following glaucoma-filtering surgery in eyes with split fixation.

Purpose: The aim of this study was to evaluate the incidence and etiology of loss of vision in the early postoperative period after glaucoma-filtration surgery in eyes with split fixation.

Methods: This was a prospective, interventional cohort study. Sixty-five eyes of 65 patients with advanced glaucomatous optic nerve damage with split fixation were included.

Comparison of saccadic reaction time between normal and glaucoma using an eye movement perimeter.

Aim: To compare the saccadic reaction time (SRT) in both the central and peripheral visual field in normal and glaucomatous eyes using eye movement perimetery (EMP).

Materials And Methods: Fifty-four normal and 25 glaucoma subjects underwent EMP and visual field testing on the Humphrey Field Analyser (HFA) 24-2 program. The EMP is based on infrared tracking of the corneal reflex.

Six-year incidence of angle-closure disease in a South Indian population: the Chennai Eye Disease Incidence Study.

Purpose: To estimate the 6-year incidence of primary angle-closure (PAC) disease among adult population aged 40 years and older from rural and urban south India.

Design: Population-based longitudinal study.

Methods: A complete ophthalmologic examination, including applanation tonometry, gonioscopy, biometry, stereoscopic fundus examination, and automated perimetry was performed at both baseline and at the 6-year follow up at base hospital.

Outcomes of bleb excision with free autologous conjunctival patch grafting for bleb leak and hypotony after glaucoma filtering surgery.

Purpose: To determine the outcomes of bleb excision with free autologous conjunctival patch grafting for bleb leak and hypotony after glaucoma filtering surgery.

Patients And Methods: Retrospective, consecutive, noncomparative case series. Outcome measures were closure of bleb leak, intraocular pressure (IOP), and best corrected visual acuity after patch grafting and complications from intervention.

Binocular potential score: a novel concept.

Objective: To assess the predictive value of an objective system for preoperative binocular potential scoring on the postoperative outcome in horizontal concomitant strabismus.

Methods: A prospective interventional study of 100 patients undergoing surgery for horizontal concomitant strabismus was conducted. The binocular potential score (BPS) was evaluated on the basis of age of onset, duration, intermittency, variability, vision, and responses on synoptophore and Worth four-dot test.