Cefiderocol (FDC), a novel siderophore drug, is active against Gram-negative bacteria producing carbapenemases, including metallo-beta-lactamases. The objective of this study is to compare the activity of FDC with ceftazidime-avibactam (CZA), CZA/aztreonam (AT) combination, and colistin (CST), in clinical isolates of meropenem-resistant (MER-R) . From the 2,052 clinical specimens submitted for culture testing, 245 .
View Article and Find Full Text PDFBackground Accurate interpretation of antibiotic susceptibility testing (AST) is one of the most crucial functions of the microbiology laboratory. However, its performance depends on a number of critical factors. We conducted a status survey to understand the existing practices in Indian laboratories that have a potential to influence performance of AST.
View Article and Find Full Text PDFBackground: There was evidence that antibiotic usage increased in hospitalized COVID-19 patients during the early days of the pandemic.
Objective: We assessed the impact of stewardship interventions on antibiotic usage in these patients.
Methods: We designed a quasi-experimental study using an interrupted time series.