Publications by authors named "Mang S"

Fungi belonging to the genus have received high consideration in agriculture due to their beneficial effects on crops from their plant promotion effects and protection from disease. A role of fungi in triggering plant defense mechanisms against insect pests, either directly or by natural enemy attraction, has been proposed, even if the results in different studies are controversial. In this present study, using zucchini plants as a model species, we investigated the effects of strain T22 plant inoculation on the cotton aphid and its endoparasitoid .

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Target values for arterial carbon dioxide tension (PaCO 2 ) in extracorporeal membrane oxygenation (ECMO) for acute respiratory distress syndrome (ARDS) are unknown. We hypothesized that lower PaCO 2 values on ECMO would be associated with lighter sedation. We used data from two independent patient cohorts with ARDS spending 1,177 days (discovery cohort, 69 patients) and 516 days (validation cohort, 70 patients) on ECMO and evaluated the associations between daily PaCO 2 , pH, and bicarbonate (HCO 3 ) with sedation.

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The acute respiratory failure as well as ARDS (acute respiratory distress syndrome) have challenged clinicians since the initial description over 50 years ago. Various causes can lead to ARDS and therapeutic approaches for ARDS/ARF are limited to the support or replacement of organ functions and the prevention of therapy-induced consequences. In recent years, triggered by the SARS-CoV-2 pathogen, numerous cases of acute lung failure (C-ARDS) have emerged.

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Article Synopsis
  • ARDS is a serious condition, impacting over 10% of ICU patients globally with a high mortality rate, making ECMO a potentially vital, but complex, treatment option.
  • Recent research analyzed 283 ARDS patients treated with V-V ECMO in Germany, revealing a median age of 56 and an in-hospital mortality rate of about 50.9%.
  • While various scoring systems were evaluated for predicting patient outcomes, the study concluded that none, including the Simplified Acute Physiology Score-II, demonstrated strong predictive value for selecting patients suitable for ECMO.
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  • Researchers are studying a special type of bacteria called DSPZPP1, found in traditional sausages from Southern Italy, because it's safe and might be helpful in food!
  • They looked at the entire DNA of this bacteria and found it can make important vitamins and some useful substances that can help in food production!
  • They also discovered that DSPZPP1 is safe for humans, doesn’t carry harmful genes, and is closely related to other types of bacteria studied before!
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Manual separation of egg yolk from egg white using the eggshell is common practice in private households. For this, the egg is cracked and both components are separated by passing the egg yolk back and forth between the two halves of the eggshell, allowing the egg white to drip down while the egg yolk remains in the shell. During this process, the egg content naturally gets in contact with the outside of the eggshell, which might lead to a cross-contamination with its microorganisms, thus was correspondingly assessed in this study.

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Growth of meat microbiota usually results in spoilage of meat that can be perceived by consumers due to sensory changes. However, a high bacterial load does not necessarily result in sensory deviation of meat; nevertheless, this meat is considered unfit for human consumption. Therefore, the aims of this study were to investigate changes in the microbiota from fresh to spoiled meat and whether the proportions of certain bacteria can probably be used to indicate the hygiene status of meat.

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  • ECMO is a life-saving treatment for patients with severe lung injuries, but sometimes it fails to improve low oxygen levels in the blood.
  • Some patients have been treated with a second membrane lung connected either in series (one after the other) or in parallel (side by side) to help with this issue, but it's unclear which method works better.
  • Testing showed that using two lungs in a series configuration was 17% more effective at transferring oxygen compared to a parallel setup, but more research is needed before this approach can be widely adopted due to its invasive nature.
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Ecological farming is increasing worldwide, as more and more consumers prefer chemical-free fruits. As a result, ecological farming is becoming increasingly appealing to European farmers, including those in Romania. However, implementing an effective ecological phytosanitary program remains a challenge for farmers due to limited options and a lack of information about their effectiveness.

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Venovenous extracorporeal membrane oxygenation (VV-ECMO) is predominantly being used as a rescue strategy in patients with acute lung failure, suffering from severe oxygenation and/or decarboxylation impairment. Cannulas introduced into the central veins lead blood through a membrane oxygenator in which it is oxygenated via sweep gas (pO up to 600 mm Hg) flow, eliminating CO. According to the largest randomized studies carried out so far, the two most important indications for VV-ECMO are hypoxic respiratory failure (paO2 < 80 mm Hg for more than 6 h) and refractory hypercapnia (pH < 7.

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Article Synopsis
  • Interhospital transport of ARDS patients using mobile ECMO units does not increase mortality risks for COVID-19 patients compared to those treated at established ECMO centers.
  • Overall patient characteristics were similar in terms of age, sex, and health scores, suggesting comparable conditions for both transport groups.
  • The study recommends early referral of suitable COVID-19 patients with ARDS to local ECMO centers for optimized care, as transport outcomes align with those treated at specialized facilities.
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Critically ill patients in need of specialized diagnostic or therapeutic procedures, but are being cared for in a hospital without such equipment, have to be transferred to appropriate centers without discontinuation of current critical care (interhospital critical care transfer). These transfers are resource intensive, challenging, and require high logistical effort, which must be managed by a specialized and highly trained team, predeployment planning and efficient crew-resource management strategies. If planned adequately, interhospital critical care transfers can be performed safely without frequent adverse events.

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The investigation focused on the deterioration of the walls in the hypogeum of "San Pietro Barisano" rupestrian church, located in the Matera-Sassi (Southern Italy), one of the UNESCO World Heritage sites. The study evaluated the biocide activity of a mixture of natural glycoalkaloids (GAs) extracted from the unripe fruit of and applied to clean a hypogeum wall surface in the church affected by bio-patinas. The analyzed bio-patina, collected before treatment and, at pre-established times, after treatment, showed changes in chemical composition detected by XPS, accompanied by visible discoloration and biological activity variation.

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Article Synopsis
  • Critically ill patients sometimes need to be moved from one hospital to another to access specialized care, which requires ongoing critical care during transfer.
  • *These transfers are complex, demanding careful planning and a skilled team to minimize risks and ensure patient safety.
  • *Additionally, there are unique scenarios, like transfers for quarantine patients or those requiring special equipment, that require adjustments in team structure and resources.
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Agrochemicals are generally used in agriculture to maximize yields and product quality, but their overuse can cause environmental pollution and human health problems. To reduce the off-farm input of chemicals, numerous biostimulant products based on beneficial symbiont plant fungi are receiving a great deal of attention. The evolution of plant diseases and the performance of insects are influenced by plant chemical defences, both of which are, in turn, influenced by below-ground symbionts.

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There is ongoing debate whether lung physiology of COVID-19-associated acute respiratory distress syndrome (ARDS) differs from ARDS of other origin. : The aim of this study was to analyze and compare how critically ill patients with COVID-19 and Influenza A or B were ventilated in our tertiary care center with or without extracorporeal membrane oxygenation (ECMO). We ask if acute lung failure due to COVID-19 requires different intensive care management compared to conventional ARDS.

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The antioxidant and antimicrobial activities of L. and Cham. mother tinctures against a range of foodborne bacteria were investigated to determine the major components and to analyse the action spectrum and antimicrobial effectiveness of the extracts.

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Pure isolates of Clostridium spp. are required when further investigations are needed, such as the characterisation of the colonies, sporulation and germination, biochemical analysis, growth rate and growth conditions, toxin production, spoilage potential and genomic profile. However, the isolation of cold-tolerant Clostridium spp.

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Article Synopsis
  • Early prognosis of COVID-19 severity can be improved using specific biomarkers like TRAIL, IP-10, and CRP for patient care.
  • In a study with 132 COVID-19 patients, it was found that TRAIL levels were significantly lower, while IP-10 and CRP levels were higher compared to healthy controls, indicating potential links to disease severity.
  • Multivariable analysis revealed obesity, CRP, and peak IP-10 levels as independent predictors of mortality in ICU, suggesting their importance in assessing patient outcomes.
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Val d'Agri is an important orchard area located in the Basilicata Region (Southern Italy). A phenomenon affecting cv. "Golden Delicious" apples which lead to tree death has been observed in the past several years in this area.

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Fungi belonging to the genus have received much attention in recent years due to their beneficial effects on crop health and their use as pest control agents. activates direct plant defenses against phytophagous arthropods and reinforces indirect plant defense through the attraction of predators. Although the plant defenses against insect herbivores were demonstrated in laboratory experiments, little attention has been paid to the use of spp.

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