Publications by authors named "Manfred Peter Wirth"

Article Synopsis
  • The study compared oncological outcomes between open radical nephroureterectomy (ORNU) and laparoscopic radical nephroureterctomy (LRNU) in patients with upper tract urothelial carcinoma (UTUC).
  • Utilizing a multi-institutional database of 3,984 patients, propensity score matching was applied to adjust for preoperative factors like age and gender.
  • Findings indicated that while LRNU had an increased risk of overall recurrence, it showed a protective effect against cancer-specific mortality; however, after adjusting for confounding variables, no significant differences in outcomes were found between the two approaches.
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Objective: To evaluate the incidence and survival outcomes of histological variants of upper tract urothelial carcinoma (UTUC) treated with radical nephroureterectomy (RNU).

Materials And Methods: We retrospectively analysed data from 1610 patients treated with RNU for clinically non-metastatic UTUC between 1990 and 2016 in several centres participating in the UTUC Collaboration. Histological variants were classified as micropapillary, squamous, sarcomatoid and other, including other rare variants (<10 cases for each).

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Introduction: To evaluate temporal trends in the delivery and extent of lymphadenectomy (LND) in radical nephroureterectomy (RNU) performed in upper tract urothelial carcinoma (UTUC) patients.

Methods: We evaluated a multi institutional collaborative database composed by 1512 consecutive patients diagnosed with UTUC treated with RNU between 1990 and 2016. Year of surgery were grouped in five periods: 1990-1996, 1997-2002, 2003-2007, 2008-2012 and 2013-2016.

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