Chem Biodivers
December 2024
Plant-derived essential oils (EO) offer a natural alternative to chemical pesticides for eco-friendly pest control approaches. Aceria pongamiae Keifer, a notorious pest that affects Pongamia pinnata (L.) Pierre has mainly been controlled using synthetic acaricides leading to resistance development and environmental issues.
View Article and Find Full Text PDFReducing the activity of cytokines and leukocyte extravasation is an emerging therapeutic strategy to limit tissue-damaging inflammatory responses and restore immune homeostasis in inflammatory diseases. Proteoglycans embedded in the vascular endothelial glycocalyx, which regulate the activity of cytokines to restrict the inflammatory response in physiological conditions, are proteolytically cleaved in inflammatory diseases. Here we critically review the potential of proteolytically shed, soluble vascular endothelial glycocalyx proteoglycans to modulate pathological inflammatory responses.
View Article and Find Full Text PDF