Publications by authors named "Mandy W M Chan"
Article Synopsis
- The study evaluated a new dermal cooling system (DCS) for treating benign pigmented lesions in Asian patients, focusing on its effectiveness and side effects.
- Patients received up to 10 sessions of DCS treatment, showing significant improvements in lesions at 2, 6, and 12 months after treatment.
- The results indicated that DCS was effective and safe with only minor side effects, making it a promising option for this type of skin treatment.
Background And Objectives: Fractional radiofrequency devices have been demonstrated to improve skin texture, such as smoothness, rhytides, brightness, and atrophic acne scars, by increasing dermal thickness, dermal collagen content, and dermal fibrillin content. The objective of the study is to assess the efficacy and adverse effects of this device on Asian patients of skin type III and IV with skin textural changes.
Materials And Methods: The study was designed as a prospective, open-labeled single-arm study, which was conducted with 20 Chinese patients aged 21-60 years and having irregularities in their skin texture, rhytides, and acne scars.
Background And Objectives: Facial melasma is a disfiguring pigmentation and occurs frequently with aging skin. Topical treatment alone was often suboptimal. A recent study showed that fractional picosecond laser has promising result in benign pigmentary lesions.
View Article and Find Full Text PDFThe aim of this study was to identify key microbes associated with change in skin status (lesional vs normal). Longitudinal changes in the skin microbiome between patients with psoriasis and healthy family controls living in the same household were studied using whole genome metagenomic shotgun sequencing at 4 time-points. There were significant changes in abundance of the pathogen Campylobacter jejuni and its higher taxonomic levels when the skin status of patients with psoriasis changed.
View Article and Find Full Text PDFBackground And Objective: To evaluate safety and efficacy of treatment with the picosecond Nd:YAG 532 nm for lentigines in Asian skin.
Study Design/materials And Methods: This was a prospective, open-label cohort study, using a novel picosecond 532-nm laser for the treatment of facial lentigines. Subjects received up to three laser treatments every 4-6 weeks and were assessed at 4 and 12 weeks after final treatment.