Synopsis of recent research by authors named "Mandy S Chang"
- Mandy S Chang's recent research primarily focuses on cardiovascular disease mechanisms, specifically utilizing the apolipoprotein E-deficient rat model to investigate conditions like atherosclerosis and abdominal aortic aneurysms (AAAs).
- In her 2018 study, she examined whether angiotensin II infusion would induce abdominal aortic aneurysms in apolipoprotein E-deficient rats, a hypothesis based on evidence from similar mouse models.
- The findings revealed that angiotensin II infusion does not result in the development of dissecting abdominal aortic aneurysms in these rats, suggesting important distinctions between rat and mouse models in AAA research.
