Publications by authors named "Mandy Lui"
Article Synopsis
- Antibiotics are frequently prescribed for respiratory infections in primary care despite evidence showing minimal benefit and a contribution to microbial resistance; point-of-care tests could help reduce unnecessary prescriptions.
- A randomized controlled trial is being conducted in the UK with participants providing swab samples and being assigned to either receive a rapid microbiological test or standard care to assess the impact on antibiotic prescribing.
- The study will evaluate antibiotic prescription rates, patient symptom tracking, and follow-up medical records over six months, aiming to recruit 514 patients to achieve strong statistical validity.
Article Synopsis
- Adalimumab is being tested as a treatment for autoimmune non-infectious uveitis (ANIU) in a trial called ASTUTE, which aims to evaluate its effectiveness and cost-effectiveness for a broader range of patients than currently approved in the UK.
- The trial is a multicenter, placebo-controlled study, where 174 participants who respond to a 16-week run-in phase will be randomized to receive either adalimumab or placebo, focusing on treatment failure and various outcomes like visual function and quality of life.
- Ethical approval was obtained in June 2020, and the results of the trial will be shared at international conferences and published in peer-reviewed journals to ensure widespread dissemination among professionals and patients.
This study was undertaken to measure and compare the thickness and cross-sectional area of the Achilles tendon between frequent- and infrequent-exercise subjects, and between the dominant and nondominant ankles in an asymptomatic Chinese population. Interobserver variability in the measurement of the size of Achilles tendon was also evaluated. High-resolution ultrasound (US) examination of Achilles tendons was performed in 40 healthy subjects (20 who frequently exercised, had exercise at least 3 days per week and at least 2 h per session; and 20 who infrequently exercised); their age range was 19 to 25 years.
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