Publications by authors named "Mandy L Wallace"

Objectives: The objective of this study was to describe the all-cause mortality rate in cats hospitalized by the soft tissue surgery service of an academic referral hospital over a 5-year period and to identify specific risk factors for mortality. The hypotheses were that the all-cause mortality rate during hospitalization would be low, and cats undergoing emergency surgery and those with an American Society of Anesthesiologists (ASA) status of 3 or more would be at increased risk for mortality.

Methods: The case log of cats hospitalized by the soft tissue surgery service at the University of Georgia was searched retrospectively to identify all cats hospitalized in the years 2015-2020.

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Objective: To assess outcomes of dogs with side-to-side portocaval extrahepatic portosystemic shunts (PC-EHPSS) and poor portal perfusion to the liver treated with medical management alone (MM) or surgical attenuation (SA).

Study Design: Multi-institutional retrospective study.

Animals: A total of 21 dogs with PC-EHPSS (14/21 MM and 7/21 SA).

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Objective: To determine the rates of wound healing in surgically created wounds between nitric oxide releasing wound dressings and control wound dressings.

Study Design: Prospective, controlled, randomized experimental study.

Animals: Purpose-bred, adult, male Beagles (n = 6).

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Article Synopsis
  • The study looked at dogs with liver tumors to see if their blood clotting times (PT and aPTT) were longer than normal before surgery.
  • Out of 359 dogs, 74 had longer PT or aPTT, and 20 had both, but only dogs with a type of tumor called hemangiosarcoma showed both problems together.
  • The results suggest that testing for these blood clotting times isn't very helpful for most liver tumor dogs, unless there's a strong chance they have hemangiosarcoma.
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Canine congenital extrahepatic portosystemic shunt (EHPSS) morphologies have not been fully elucidated. The goal of this retrospective, multi-institutional study was to use CT angiography to create an anatomical-based nomenclature system for canine congenital EHPSS. These shunt morphologies were then evaluated to identify any significant association with patient age, sex, breed, weight, or subjective portal perfusion score.

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Dogs with a brachycephalic conformation often experience a collection of abnormalities related to their craniofacial conformation, which can lead to a variety of clinical signs such as stertor, exercise intolerance, respiratory distress, and gastrointestinal signs such as regurgitation, among others. This collection of abnormalities is termed brachycephalic obstructive airway syndrome (BOAS). With the rise in popularity of several brachycephalic breeds, veterinarians and veterinary surgery specialists are seeing these dogs with increasing frequency for surgical and medical treatment of these clinical signs, leading to an increased interest in developing surgical techniques for dogs with BOAS and evaluating objective methods of determining outcome after surgery.

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Background: Enhanced platelet responses have been demonstrated in heartworm-infected (HWI) dogs; however, the cause and clinical implications of altered platelet function have not been fully elucidated.

Objective: This study evaluated platelet function in HWI dogs.

Methods: Anticoagulated whole blood collected from eight HWI and eight uninfected dogs was evaluated using turbidometric platelet aggregometry, a platelet function analyzer (PFA-100), a total thrombus analysis system (T-TAS), tissue factor-activated and tissue plasminogen activator modified thromboelastography (TF- and tPA-TEG), CBC, von Willebrand Factor activity, and fibrinogen concentrations.

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Objective: To assess the predictability of the hemangiosarcoma likelihood prediction (HeLP) score and the Tufts Splenic Tumor Assessment Tool (T-STAT) for hemangiosarcoma and malignancy, respectively.

Animals: 261 dogs undergoing splenectomy for a splenic mass.

Methods: Medical records were retrospectively reviewed; variables for the HeLP score and T-STAT were collected, and scores were assigned.

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The prevalence of anatomical-based subtypes of feline congenital extrahepatic portosystemic shunts (EHPSS) has not been completely elucidated. The goal of this study was to use CT angiography to create an anatomical-based nomenclature system for feline congenital EHPSS. Additionally, subjective portal perfusion scores were generated to determine if intrinsic portal vein development was associated with different shunt conformations or patient age at the time of CT.

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Objective: To report the clinical characteristics, treatments, and outcomes in a cohort of dogs with histologically confirmed retroperitoneal sarcoma (RPS) and to identify potential variables of prognostic significance.

Animals: 46 client-owned dogs from 10 clinics with histopathologic diagnosis of a sarcoma originating from the retroperitoneal space.

Methods: Medical records were retrospectively reviewed to obtain information regarding clinical characteristics, treatments, and outcomes.

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Article Synopsis
  • The study aimed to compare postoperative pain levels in dogs undergoing abdominal surgery treated with either bupivacaine liposomal injectable suspension (BLIS) or saline during incision closure.
  • A total of 40 dogs were evaluated, with pain assessed using various methods such as blood pressure measurements and the Glasgow Composite Measure Pain Scale (GCMPS).
  • Findings revealed minimal differences in pain management between the two groups, with BLIS showing slightly lower GCMPS scores at day 3 but no significant advantages in overall pain control or complication rates compared to saline.
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Objective: To describe demographics, clinical presentation, shunt anatomy, clinical progression, and complications in large dogs ≥15 kg with single extrahepatic portosystemic shunts (EHPSS) treated with or without surgery.

Study Design: Multicenter retrospective (10 university hospitals, one private referral institution).

Animals: Dogs ≥15 kg (n = 63).

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Objective: To evaluate the accuracy, precision, and observer agreement of three pressure measurement devices.

Study Design: In vitro model study.

Sample Population: Water manometer with built-in gauge (WMg), arterial pressure transducer (APT), and Compass CT (CCT).

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Objective: To identify risk factors for intra- and postoperative ventricular arrhythmias (VAs) and in-hospital mortality in dogs undergoing splenectomy for splenic masses.

Animals: 308 dogs.

Methods: Records from 2010 through 2018 were reviewed for dogs undergoing splenectomy for a splenic mass.

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Objective: To identify the frequency of and risk factors for acute kidney injury (AKI) in dogs undergoing abdominal surgery for septic peritonitis, and to evaluate outcome and kidney-related risk factors for survival to discharge in those dogs.

Animals: 77 dogs that underwent abdominal surgery for septic peritonitis.

Methods: Medical records of dogs that underwent surgery for septic peritonitis from 2012 through 2022 were reviewed.

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Objectives: Gastrointestinal foreign bodies (FBs) are an important cause of emergency surgical intervention in cats, but little information exists in the literature evaluating the risks and outcomes in this species. The study purpose was to describe cases of feline FBs and compare perioperative factors and outcomes between linear foreign body (LFB) and discrete foreign body (DFB) surgery in cats.

Methods: The medical records from the University of Georgia Veterinary Teaching Hospital were searched for cats that had undergone surgery for FB removal between August 2009 and August 2021.

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Objective: Describe clinical features and outcomes of dogs undergoing scar revision for incompletely or narrowly excised cutaneous mast cell tumors without gross disease.

Animals: 52 dogs undergoing 54 scar revisions.

Procedures: Retrospective record review with information collected on signalment, tumor type/location, pre-surgical diagnostics, surgical and pathologic findings for the first excision and scar revision surgeries, and follow-up.

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Objective: Describe clinical features of dogs undergoing scar revision for incompletely or narrowly excised soft tissue sarcomas (STSs) in the absence of gross disease and to determine local recurrence rates following scar revision.

Animals: Thirty-three dogs with 33 scars.

Procedures: Medical records were reviewed to collect data on signalment, tumor details, pre-surgical diagnostic tests, surgical and pathologic findings for both the initial and revision surgeries, and clinical outcomes.

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Complex vascular anomalies are often difficult concepts for veterinary medical students to comprehend, as knowledge of normal anatomy, visualization of the abnormal anatomy, and understanding of the physiologic implications of that abnormality are all required to appreciate the clinical impacts of the anomaly. Access to interactive 3D models of both the normal and abnormal vasculatures may improve student comprehension. In this study, third-year veterinary medical students in a core small animal digestive diseases course completed a pre-lecture assignment consisting of a text-only narrative ( = 100) or an interactive electronic book (e-book; = 102) focused on extrahepatic portosystemic shunts, followed by two generative learning activities in which they described portal anatomy and extrahepatic portosystemic shunts.

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Objective: To describe complications and outcomes of dogs undergoing thoracoscopic-assisted (TA) lung lobectomy.

Study Design: Multi-institutional, retrospective study.

Animals: Client-owned dogs (n = 30).

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Objectives: To compare neonatal survival to discharge rates between brachycephalic and nonbrachycephalic dogs undergoing cesarean section (c-section) and identify risk factors for neonatal mortality.

Study Design: Retrospective study.

Animals Or Sample Population: A total of 480 puppies from 90 bitches undergoing 106 c-sections.

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Objective: Describe clinical features, treatment, and outcomes in dogs with deep neck infections.

Animals: 19 dogs undergoing surgical treatment of deep neck infections from January 1, 2015, through December 31, 2020.

Procedures: Retrospective record review was conducted, with data collected including clinical signs; neutrophil-to-lymphocyte ratio (NLR); diagnostic imaging, surgical, and histopathologic findings; and follow-up.

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Objective: To develop a topical sildenafil hydrogel and evaluate its effect on wound healing in dogs.

Animals: 6 purpose-bred, sexually intact, adult Beagles.

Procedures: Hydrogels containing sildenafil citrate, N-methyl-2-pyrrolidone, propylene glycol, and poloxamer 407 were developed.

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Background: Canine intrarenal cystic lesions (ICLs) are infrequently reported in the veterinary literature. Several treatment options have been described including cyst fenestration (partial nephrectomy/deroofing) +/- omentalization, sclerotherapy using alcohol as a sclerosing agent, percutaneous cyst drainage (PCD), and ureteronephrectomy. Information regarding presenting clinical signs, physical examination findings, histologic diagnosis and outcomes of dogs with ICLs treated by different methods is limited.

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Objective: To describe veterinary house officers' perceptions of dimensions of well-being during postgraduate training and to identify potential areas for targeted intervention.

Sample: 303 house officers.

Procedures: A 62-item questionnaire was generated by use of an online platform and sent to house officers at participating institutions in October 2020.

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