Publications by authors named "Mandish K Dhanjal"

Article Synopsis
  • A study examined the outcomes of 25 pregnant women treated with IL-6 receptor antibodies for COVID-19 during their pregnancies at two hospitals in London from March 2020 to September 2022.
  • Most women were in critical condition; 16 were treated in the third trimester, and all required multiple medications.
  • Results indicated no serious maternal health issues, with all pregnancies resulting in live births, although there were complications, including 16 preterm births and one neonatal death due to severe prematurity.
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Background: Ethnic disparities in maternal mortality were first documented in the UK in the early 2000s but are known to be widening. This project aimed to describe the women who died in the UK during or up to a year after the end of pregnancy, to compare the quality of care received by women from different aggregated ethnic groups, and to identify any structural or cultural biases or discrimination affecting their care.

Methods: National surveillance data was used to identify all 1894 women who died during or up to a year after the end of pregnancy between 2009 and 18 in the UK.

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Objective: To determine maternal, obstetric and neonatal outcomes in a cohort of women with cerebrovascular malformations (CVMs) that include arterial venous malformations (AVMs) and cavernomas.

Design: Retrospective cohort study.

Setting: Six specialist centres managing pregnant women with neurological disorders.

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Objective: To examine the monitoring, management, and outcomes of pituitary tumors in pregnancy.

Methods: A national, prospective, observational, population-based case series study was conducted in all U.K.

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Most published cases of cytomegalovirus infection in pregnancy relate to congenital abnormalities in neonates infected in early pregnancy, while the mother remains asymptomatic. We describe a diagnostically challenging case of an immunosuppressed woman with scleroderma who developed deranged liver function tests attributed to intrahepatic cholestasis of pregnancy and haemolysis, elevated liver enzymes and low platelets syndrome but was ultimately found to have disseminated cytomegalovirus. Cytomegalovirus can present in a myriad of ways.

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Women with medical disease have a higher incidence of maternal mortality compared with healthy women, with cardiac disease now being the most common cause of maternal death in the UK. A handful of medical conditions exist where pregnancy is not recommended due to mortality rates approaching 50%. It is imperative that such women have the most reliable methods of contraception available.

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