A prophage tail-like protein facilitates the endophytic growth of Burkholderia gladioli and mounting immunity in tomato.

A prophage tail-like protein (Bg_9562) of Burkholderia gladioli strain NGJ1 possesses broad-spectrum antifungal activity, and it is required for the bacterial ability to forage over fungi. Here, we analyzed whether heterologous overexpression of Bg_9562 or exogenous treatment with purified protein can impart disease tolerance in tomato. The physiological relevance of Bg_9562 during endophytic growth of NGJ1 was also investigated.

Unifocal Gastric Langerhans Cell Histiocytosis in a Child-A Unique Case to Remember.

Langerhans cell histiocytosis (LCH) is the most common of the histiocytic disorders and occurs when the body accumulates too many CD1a/CD 207 positive Langerhans cells, a subset of the histiocytes in certain parts of the body where they can form tumors or damage organs. LCH is not a very common diagnosis in the pediatric age group. More than two-thirds of cases have the single-system disease with bones or skin as the commonly involved sites.

Evaluating Low-Carbon Transportation Technologies When Demand Responds to Price.

The carbon intensity (CI) of travel is commonly used to evaluate transportation technologies. However, when travel demand is sensitive to price, CI alone does not fully capture the emissions impact of a technology. Here, we develop a metric to account for both CI and the demand response to price (DR) in technology evaluation, for use by distributed decision-makers in industry and government, who are becoming increasingly involved in climate change mitigation as the costs of lower-carbon technologies fall.

Macrophage activation syndrome in pediatrics: 10 years data from an Indian center.

Aims: Macrophage activation syndrome (MAS) is a dreaded complication of systemic inflammatory diseases and is most commonly seen in systemic juvenile idiopathic arthritis (sJIA). We evaluate the clinical features, laboratory findings and outcomes in pediatric MAS, assess the response to different pharmacological therapies, and finally identify possible factors associated with an unfavorable outcome.

Methods: This is a retrospective analysis of data from patients diagnosed as having MAS, admitted between July 2008 and April 2018 into the Department of Pediatric Rheumatology, Institute Of Child Health Kolkata.