Publications by authors named "Mandi Winkis"
Article Synopsis
- SARS-CoV-2 vaccinations have decreased hospitalization and death rates in nursing home residents, but effectiveness is challenged by new variants and reduced immunity.
- A study evaluated the immune response to the XBB.1.5 monovalent vaccine in nursing home residents and healthcare workers, focusing on those with prior infections.
- Results showed a significant increase in neutralizing antibody levels, especially in nursing home residents who had a previous infection, indicating the vaccine's ability to enhance immunity against Omicron variants.
Background: SARS-CoV-2 vaccination has reduced hospitalization and mortality for nursing home residents (NHRs). However, emerging variants coupled with waning immunity, immunosenescence, and variability of vaccine efficacy undermine vaccine effectiveness. We therefore need to update our understanding of the immunogenicity of the most recent XBB.
View Article and Find Full Text PDF