Low micronutrient intake in nursing home residents, a cross-sectional study.

Low intake of micronutrients is associated with health-related problems in nursing home residents. As their food intake is generally low, it is expected that their micronutrient intake will be low as well. The nutrient intake of 189 residents (mean age 85.

Osteological, multi-isotope and proteomic analysis of poorly-preserved human remains from a Dutch East India Company burial ground in South Africa.

Skeletal remains discovered in Simon's Town, South Africa, were hypothesised as being associated with a former Dutch East India Company (VOC) hospital. We report a novel combined osteological and biochemical approach to these poorly-preserved remains. A combined strontium (Sr/Sr), oxygen (δO) and carbon (δC) isotope analysis informed possible childhood origins and diet, while sex-specific amelogenin enamel peptides revealed biological sex.

Too low protein and energy intake in nursing home residents.

Objectives: An optimal diet contributes to reducing malnutrition prevalence in the nursing home population. For this population, recommended daily intakes are ≥1.0 g protein/kg body weight and ≥27 energy kcal/kg body weight.

GLIM in nursing homes; practical implications.

Background: Only very few papers have described malnutrition prevalence rates according to the Global Leadership Initiative on Malnutrition (GLIM) criteria in nursing homes, likely due to practical reasons such as missing data on body composition, dietary intake, or acute disease/inflammation.

Methods: Data was collected in 5 different nursing homes. Food intake measurements took place over 3 days of observations, and intakes below 90% of energy or protein requirements were regarded as insufficient.

Malnutrition Prevalence Rates among Dutch Nursing Home Residents: What Has Changed over One Decade? A Comparison of the Years 2009, 2013 and 2018.

Objectives: To assess changes in prevalence of malnutrition and its associated factors among people living in Dutch nursing homes in 2009, 2013 and 2018.

Design: Secondary data analysis of the International Prevalence Measurement of Care Quality (LPZ) study.

Setting: Dutch nursing homes.

Glycemic Control for Colorectal Cancer Survivors Compared to Those without Cancer in the Dutch Primary Care for Type 2 Diabetes: A Prospective Cohort Study.

Cancer survivors with diabetes tend to have worse glycemic control after their cancer diagnosis, which may increase the risk of cardiovascular diseases. We aimed to investigate whether glycemic control differs between colorectal cancer (CRC) survivors and those without cancer, among patients with type 2 diabetes being treated in the Dutch primary care. The Zwolle Outpatient Diabetes project Integrating Available Care database was linked with the Dutch Cancer Registry ( = 71,648, 1998-2014).

[Metformin-associated lactic acidosis: an insufficiently recognised problem].

Metformin-associated lactic acidosis (MALA) is a rare but potentially fatal condition that can easily be avoided. As metformin is known to facilitate the production of lactate, predisposing factors can accelerate this process. In situations of infection or dehydration, metformin can accumulate due to kidney failure, hereby increasing the risk of MALA.

Endometrial injury for pregnancy following sexual intercourse or intrauterine insemination.

Background: Intentional endometrial injury is currently being proposed as a technique to improve the probability of pregnancy in women undergoing assisted reproductive technologies (ART) such as in vitro fertilisation (IVF). Endometrial injury is often performed by pipelle biopsy or a similar technique, and is a common, simple, gynaecological procedure that has an established safety profile. However, it is also known to be associated with a moderate degree of discomfort/pain and requires an additional pelvic examination.

Timed intercourse for couples trying to conceive.

Background: Fertility problems are very common, as subfertility affects about 10% to 15% of couples trying to conceive. There are many factors that may impact a couple's ability to conceive and one of these may be incorrect timing of intercourse. Conception is only possible from approximately five days before up to several hours after ovulation.

Evaluation of the Siemens VERSANT® CT/GC DNA 1.0 assay (kPCR) for detection of Chlamydia trachomatis and Neisseria gonorrhoeae.

The Siemens VERSANT kPCR system is an automated system which combines extraction of nucleic acids from 96 samples with subsequent real-time PCR. The VERSANT CT/GC DNA 1.0 (kPCR) assay detects Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (GC) in a multiplex real-time PCR on this system.

The effect of a nutrient dense drink on mental and physical function in institutionalized elderly people.

Objectives: To determine whether in the current study the supply of a nutrient dense drink has a positive effect on mental and physical function of institutionalized elderly people.

Design: A 24-week, randomized, double-blind, placebo-controlled, parallel-group, intervention trial.

Setting: Homes for the elderly and nursing homes in the Netherlands.

Effect of a nutrient-enriched drink on dietary intake and nutritional status in institutionalised elderly.

Objective: (1) To determine whether nutritional supplementation (energy and micronutrients) in institutionalised elderly has a positive effect on dietary intake and nutritional status. (2) To investigate whether individuals tend to compensate for the energy content of the intervention product by decreasing their habitual food consumption.

Methods: A 24-week, randomised, double-blind, placebo-controlled, intervention trial in homes for the elderly (n=3), in nursing homes (n=3) and 'mixed' homes (n=3) in The Netherlands.

Gamma Knife radiosurgery as a primary treatment option for solitary brain metastases from ovarian carcinoma.

We present three patients with brain metastasis cases from ovarian carcinoma (BMOC) treated at William Beaumont Hospital with a median follwow-up of 77 months and a mean survival after brain involvement of 23.66 months (range 5-44). Clinical and physical aspects are presented.

Bacille Calmette-Guérin vaccine-induced disease in HIV-infected and HIV-uninfected children.

Background: Bacille Calmette-Guérin (BCG)--a live, attenuated vaccine--is routinely given to neonates in settings where tuberculosis is endemic, irrespective of human immunodeficiency virus (HIV) exposure. HIV-infected infants and other immunodeficient infants are at risk of BCG-related complications. We report the presentation, treatment, and mortality of children who develop BCG disease, with emphasis on HIV-infected children.

Homocysteine and cognitive function in institutionalised elderly A cross-sectional analysis.

Background: Several cross-sectional, case-control and prospective studies revealed a relation between homocysteine and cognitive function or dementia. These studies included either patient populations or healthy, community- dwelling elderly people.

Aim Of The Study: In this study we tested the hypothesis that homocysteine was inversely associated with cognitive function in a population of institutionalised elderly (aged >/= 60 y; n = 157).

Effectiveness of nutritional supplements on cognitive functioning in elderly persons: a systematic review.

Background: The effectiveness of nutritional supplementation in improving cognitive functioning is evaluated in elderly people.

Methods: The authors systematically reviewed randomized controlled trials that compared nutritional supplementation with a placebo treatment. Trials were identified from a MEDLINE search and from reference lists of identified studies and review articles.

Effect of 8 week intake of probiotic milk products on risk factors for cardiovascular diseases.

Objective: To investigate the effect of a probiotic milk product containing the culture CAUSIDO(R) and of two alternative products on risk factors for cardiovascular disease in overweight and obese subjects.

Design: An 8 week randomized, double-blind, placebo- and compliance-controlled, parallel study.

Subjects: Seventy healthy, weight-stable, overweight and obese (25.

The effects of maternal exercise on fetal heart rate and movement patterns.

The aim of this study was to investigate the effects of maternal exercise on fetal movement and heart rate patterns. Twelve healthy women at 29-32 weeks of pregnancy performed a (sub)maximal bicycle exercise test, reaching 53-99% (median 82%) of their maximal increase in heart rate (MIHR). Fetal heart rate (FHR) and its variation and fetal body and breathing movements were recorded for 1 h before and after the exercise and also on a control day.

Elimination of nasal carriage of Staphylococcus aureus in hemodialysis patients.

Objective: To study the efficacy of mupirocin for the elimination of nasal carriage of Staphylococcus aureus in hemodialysis patients.

Design: The efficacy of mupirocin was studied in a prospectively followed cohort. The effect of this intervention on the rate of S aureus bacteremia was evaluated using a historic control group.

Reduction of surgical-site infections in cardiothoracic surgery by elimination of nasal carriage of Staphylococcus aureus.

Objective: To test the hypothesis that perioperative elimination of nasal carriage of Staphylococcus aureus using mupirocin nasal ointment reduces the surgical-site infection (SSI) rate in cardiothoracic surgery.

Design: Unblinded intervention trial with historical controls.

Setting: A university hospital, tertiary referral center for cardiothoracic surgery.

Surveillance of postoperative infections in thoracic surgery.

Postoperative infections (PIs) are serious complications of thoracic surgery. To gain insight into the nature and the scope of the problem, an 18-month prospective surveillance was conducted at the department of thoracic surgery of the University Hospital Rotterdam, Dijkzigt. PI were classified according to CDC criteria.