In this study, the spectrophotometric method integrated with continuous wavelet transform (CWT) and coupled discrete wavelet transform (DWT) with fuzzy inference system (FIS) was developed for the simultaneous determination of ethinyl estradiol (EE) and drospirenone (DP) in combined oral contraceptives (COCs). The CWT approach was performed in the linearity range of 0.6-6 µg/mL for EE and 0.
View Article and Find Full Text PDFBackground: Spectrophotometry alone is not applicable for the simultaneous determination of drugs in a multicomponent pharmaceutical formulation owing to their overlap.
Objective: In this study, the combination of UV-Vis spectrophotometry and chemometric methods, including continuous wavelet transform (CWT) and partial least-squares (PLS) was presented for the simultaneous estimation of tamsulosin (TAM) and solifenacin (SOL) in synthetic mixtures, commercial formulations, and a biological sample.
Methods: The simultaneous spectrophotometric determination of TAM and SOL in binary mixtures, a real sample, and a biological sample was performed by applying CWT and PLS approaches.
In this research the influence of the silica supported calix[4]arene derivative (SS-Calix) on the reversion resistance, mechanical properties and thermal behavior of NR/BR tire tread formulation was investigated by the oscillating disc rheometer, FTIR, TGA and tensile testing. The results revealed that the reversion behavior of NR/BR vulcanizate is affected by SS-Calix. The data obtained from curing characteristics and thermal stability of test pieces indicate that, SS-Calix acts as an anti-reversion for rubbery materials that are exposed to thermal shock in the early stages of temperature rise.
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