Publications by authors named "Manchon-Walsh P"

Background: Multidisciplinary team meetings (MTMs) are considered a pillar of cancer care; however, evidence of the independent benefit of MTMs on survival in rectal cancer is controversial.

Methods: This population-based cohort analysis included patients undergoing surgery for primary rectal cancer with curative intent. We drew data derived from three clinical audits conducted in Catalonia from 2011 to 2020.

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Background: The Catalan Cancer Plan (CCP) undertakes periodic audits of cancer treatment outcomes, including organ/space surgical site infections (O/S-SSI) rates, while the Catalan Healthcare-associated Infections Surveillance Programme (VINCat) carries out standardized prospective surveillance of surgical site infections (SSI) in colorectal surgery. This cohort study aimed to assess the concordance between these two monitoring systems for O/S-SSI following primary rectal cancer surgery.

Methods: The study compared O/S-SSI incidence data from CCP clinical audits versus the VINCat Programme in patients undergoing surgery for primary rectal cancer, in 2011-12 and 2015-16, in publicly funded centres in Spain.

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Aim: Few published studies comprehensively describe the characteristics of patients with pancreatic cancer and their treatment in clinical practice. This study aimed to describe the current clinical practice for treating pancreatic cancer in Catalonia, along with the associated survival and treatment costs.

Methods: A retrospective observational cohort study in patients diagnosed with pancreatic cancer from 2014 to 2018, using data from the healthcare records of the Public Health System of Catalonia, was conducted.

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The centralization of complex surgical procedures for cancer in Catalonia may have led to geographical and socioeconomic inequities. In this population-based cohort study, we assessed the impacts of these two factors on 5-year survival and quality of care in patients undergoing surgery for rectal cancer (2011-12) and pancreatic cancer (2012-15) in public centers, adjusting for age, comorbidity, and tumor stage. We used data on the geographical distance between the patients' homes and their reference centers, clinical patient and treatment data, income category, and data from the patients' district hospitals.

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Objective: To assess the impact of prehospital factors (diagnostic pathways, first presentation to healthcare services, intervals, participation in primary care) on 1-year and 5-year survival in people with epithelial ovarian cancer (EOC).

Design: Retrospective quasi-population-based cohort study.

Setting: Catalan Integrated Public Healthcare System.

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Background: Centralisation of cancer surgery is a commonly applied healthcare strategy worldwide. This study aimed to detail the design of centralisation policies, to shed light on the implications of such policies in real practice and to describe the different perspectives taken to deal with difficulties that emerged, taking pancreatic cancer as an example of a complex cancer disease requiring surgery.

Methodology: A scoping review was conducted using the MEDLINE database.

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Background: The clinical value of transanal total mesorectal excision is debated.

Objective: This study aimed to compare short- and medium-term effects of transanal versus anterior total mesorectal excision for rectal cancer.

Design: This was a multicenter retrospective cohort study.

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Objective: To assess adherence to endocrine therapy and its relation to recurrence and mortality in women with early breast cancer.

Methods: This is a retrospective cohort study in population-based cancer registries in two Catalonian provinces of Spain. We included all cases of invasive stage I-III breast cancer diagnosed from 2007 to 2011 and with follow-up to 2017.

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Aim: The oncological risk/benefit trade-off for laparoscopy in rectal cancer is controversial. Our aim was to compare laparoscopic vs open surgery for resection of rectal cancer, using unselected data from the public healthcare system of Catalonia (Spain).

Methods: This was a multicentre retrospective cohort study of all patients who had surgery with curative intent for primary rectal cancer at Catalonian public hospitals from 2011 to 2012.

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Background: Population ageing is a relevant concern in people diagnosed with rectal cancer. This study evaluates the adherence to clinical practice guidelines (CPGs) and patient outcomes in rectal cancer, with a particular focus on variation according to age.

Methods: This is a multicentre retrospective cohort study of all patients surgically treated for the first time for primary rectal cancer with curative intent in public hospitals in Catalonia during two study periods: first, with data from 2005 to 2007, and then with data from 2011 to 2012.

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Background: Rectal cancer surgery in Catalonia has been involved in a process of centralisation. We assessed the impact of this health policy strategy on quality of care and clinical results.

Methods: We compared patterns of care and clinical outcomes of all rectal cancer patients receiving radical surgery for the first time in public hospitals in two time periods, before (2005 and 2007) and after (2011-2012) centralisation, analysing indicators of care quality according to the regional clinical practice guidelines.

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Background: The aim of centralizing rectal cancer surgery in Catalonia (Spain) was to improve the quality of patient care. We evaluated the impact of this policy by assessing patterns of care, comparing the clinical audits carried out and analysing the implications of the healthcare reform from an organizational perspective.

Methods: A mixed methods approach based on a convergent parallel design was used.

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Article Synopsis
  • The study aimed to evaluate the adherence to pre-operative radiation and chemotherapy (RT/ChT) guidelines for stage-II and -III rectal cancer patients in Catalonia, and its effect on local recurrence rates.
  • Data was collected from a multicenter retrospective cohort study involving 1,229 patients who had surgery for primary rectal cancer between 2005 and 2007, revealing that 54.5% received pre-operative RT/ChT, with a local recurrence rate of 4.1% over two years.
  • The findings indicate that patients who did not receive RT had a significantly higher risk of local recurrence compared to those who did, reinforcing the importance of pre-operative RT/ChT in reducing recurrence rates in rectal cancer
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Aim: Clinical practice guidelines in cancer are a relevant component of Catalonian Cancer Strategy aimed at promoting equity of access to therapy and quality of cancer care. The colorectal cancer (CRC) guideline was first published in 2003 and subsequently updated in 2008. This study examined the quality of therapy administered to patients with rectal cancer in public hospitals in Catalonia (Spain) in 2005 and 2007, according to CRC guideline recommendations.

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Aims: To assess the effect of partner smoking status on the success of a cessation program.

Design: Prospective cohort.

Setting: Smoking Cessation Unit in Hospital of Bellvitge (Hospitalet de Llobregat, Barcelona).

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Objective: To determinate the relationship between the age of smoking initiation and the success of the smoking cessation program.

Design: Prospective cohort.

Setting: Smoking Cessation Unit, in the University Hospital of Bellvitge, L'Hospitalet de Llobregat, Barcelona, Spain.

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