Corona virus versus existence of human on the earth: A computational and biophysical approach.

SARS-CoV-2 has a positive sense RNA genome of 29.9 kb in size, showing high sequence similarity to the BAT-CoV, SARS-CoV, MERS-CoV. SARS-CoV-2 is composed of 14 open reading frames (ORFs), which encodes for a total of 27 proteins divided into structural and non-structural proteins (NSPs).

Tibial articular cartilage wear in varus osteoarthritic knees: correlation with anterior cruciate ligament integrity and severity of deformity.

Tibial articular cartilage wear was assessed intraoperatively in 100 consecutive patients with varus osteoarthritis undergoing total knee arthroplasty. Severity of deformity on radiographs, integrity of the anterior cruciate ligament (ACL) at surgery, and body mass index were recorded. Posterior half of the medial tibial plateau was more commonly involved in knees with ACL deficiency; there was predominantly anteromedial involvement with an intact ACL.