Publications by authors named "Manatsu Mizuno"

Background: In terminal cancer patients, the nutritional status deteriorates due to cachexia. In this study, we performed a nutritional assessment of terminal gastrointestinal cancer patients and examined the relationship with prognosis.

Subjects And Methods: Fifty-eight patients with terminal gastrointestinal cancer who were hospitalized and treated from January 2019 to June 2022 were included.

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We experienced cases of malnutrition and vitamin B1 deficiency after gastrointestinal cancer surgery, but they had a good course after vitamin B1 administration. Case 1 is a woman in her 70s who underwent laparoscopic distal gastrectomy for gastric cancer 2 months ago. While under outpatient observation, she was found collapsed at home and urgently brought to the hospital.

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Article Synopsis
  • Robotic gastrectomy (RG) for gastric cancer (GC) has been covered by health insurance since 2018, and this study evaluated its initial results in a hospital setting from August 2022 to May 2023.
  • The analysis included 9 patients with a median age of 77, all of whom underwent distal gastrectomy, showing an operative time of about 410 minutes with minimal blood loss.
  • The findings indicated RG for GC was performed safely, with no major complications and all patients discharged in less than 9 days post-surgery.
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Here we report the case of a patient with advanced gastric cancer who presented with duodenal intramural metastasis based on the pathological results after surgery. The patient was 78-year-old female, who was referred to our department for further evaluation and treatment of upper abdominal pain. An upper gastrointestinal series demonstrated a tumor occupying the lesser curvature of the gastric body.

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A 50-year-old man presented with fecaluria and was diagnosed with sigmoid colon cancer with a colovesical fistula. Total bladder resection was determined to be necessary for curative resection at the time of diagnosis. In anticipation of bladder preservation, 6 courses of mFOLFOX6 plus panitumumab were administered after transverse colostomy, resulting in marked tumor regression and a decision to proceed with surgery.

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  • After the disease progressed despite paclitaxel treatment, he began S-1 monotherapy, which showed promising results with decreased lymph node metastases and pleural dissemination.
  • The treatment was well-tolerated, leading to over 2.5 years of long-term survival without disease progression and only mild side effects.
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We report a case of colon metastasis from gastric cancer treated by laparoscopic-assisted segmental colectomy. An 81-year-old man was undergone distal gastrectomy, D2 dissection and Billroth Ⅰ reconstruction for gastric cancer 3 years previously, with a final diagnosis of gastric cancer L, Post, Type 2, sig/por2, pT4a(SE), pN3b(30/56), H0, P0, M0, pStage ⅢC. Three years after gastrectomy, CT scan showed an elevated lesion in the transverse colon, which was suspected to be metastatic colorectal cancer on closer examination.

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  • A 79-year-old man with hepatocellular carcinoma (HCC) was preparing for surgery after a prior embolization for a rupture.
  • He experienced back pain two weeks before surgery and was diagnosed with obstructive jaundice caused by haemobilia, leading to biliary drainage.
  • After stabilizing his condition, he underwent hepatectomy, highlighting the importance of monitoring for haemobilia post-therapy.
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A 78-year-old man had undergone a laparoscopic sigmoid colon resection; left ureteral resection; and a ureteral reconstruction for sigmoid colon cancer with left ureteral invasion. The patient did not wish to undergo postoperative adjuvant chemotherapy, and he was followed up at fixed intervals. Six months after surgery, CT revealed peritoneal metastasis and liver metastasis(S6).

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A 60s man was diagnosed with advanced gastric cancer(cT4b[PAN], cN+, cM0, cStage ⅣA). He started first-line chemotherapy consisting of S-1 and cisplatin, but tumor markers remained elevated and CT showed cancer progression. He then started second-line chemotherapy consisting of ramucirumab and paclitaxel.

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Background: We analyzed the short-term outcomes and nutritional assessment of gastric cancer surgery patients who underwent exercise intervention after gastrectomy.

Materials And Method: Gastric cancer patients who underwent gastrectomy at our department from January 2021 were included in the study. Postoperative exercise intervention(lower limb training) was performed in gastric cancer patients aged 75 years or older(group H: 7 patients)and compared retrospectively with gastric cancer patients younger than 75 years(group L: 10 patients)who did not receive exercise intervention.

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We report a case of early gastric cancer with Adachi Type Ⅵ vascular anomaly treated by laparoscopic distal gastrectomy. An 81-year-old woman was admitted because of anorexia, and was diagnosed with early gastric cancer. Preoperative MDCT revealed Adachi Type Ⅵ vascular anomaly, where the hepatic artery does not appear at the superior border of the pancreas.

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Background: Chemotherapy-induced nausea and vomiting(CINV)are typical side effects caused by chemotherapy. We analyzed CINV during first-line chemotherapy for gastric cancer.

Materials And Method: Thirty-one patients who received first-line chemotherapy for gastric cancer were retrospectively assessed for CINV.

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Article Synopsis
  • * Increased size of a disseminated lesion led to a decision for laparoscopic resection surgery after an injection of indocyanine green (ICG) the day before.
  • * Intraoperative fluorescence imaging from ICG allowed for easy detection and complete removal of the disseminated lesions, indicating its usefulness in surgery for HCC.
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We report a case of advanced gastric cancer that was successfully treated with mFOLFOX6 therapy. A 78-year-old man presented to our hospital with a chief complaint of weight loss. Esophagogastroduodenoscopy(EGD)and computed tomography( CT)revealed the presence of type 3 advanced gastric cancer with distant lymph node metastasis and peritoneal dissemination.

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