A retrospective cohort study of major adverse cardiac events in children affected by Kawasaki disease with coronary artery aneurysms in Thailand.

Kawasaki disease (KD) is a common form of vasculitis in children that can be complicated by coronary artery aneurysms (CAAs). Data of long-term outcomes and major adverse cardiac events (MACE) in children with CAAs following KD in developing country are limited. Our aims were to determine the rates of MACE and identify risk factors associated with MACE in children with KD and CAAs in Thailand.

Assessment of Chromosome 22q11.2 Deletion in Patients with Isolated Cleft Palate: A Systematic Review of Prospective Studies.

Background: The prevalence of 22q11.2 deletion in patients presenting with isolated cleft palate has not been systematically assessed.

Objective: To assess the evidence in the literature for the prevalence of 22q11.

Birth Prevalence of Chromosome 22q11.2 Deletion Syndrome: A Systematic Review of Population-Based Studies.

Background: A birth prevalence of chromosome 22q11.2 deletion syndrome among population-based reports has been documented to vary, however, a systematic assessment is lacking.

Objective: To assess the evidence in the literature for the birth prevalence of chromosome 22q11.

Effectiveness and Safety of Radioactive Iodine Therapy in Childhood Graves’ Disease in Khon Kaen, Thailand.

Background: Graves’ disease (GD) is the most common cause of hyperthyroidism in children and adolescents. Treatments consist of medication, radioactive iodine (RAI) therapy and surgery. Currently, radioactive iodine therapy is the first line treatment in many medical centers.

INCREASED LEVELS OF MEDIAN URINARY IODINE EXCRETION OF PRIMARY SCHOOL CHILDREN IN THE SUBURBAN AREA, KHON KAEN, THAILAND.

Iodine deficiency disorder (IDD) is associated with a low IQ in children and is an important public health problem in northeastern Thailand. Despite campaigns to reduce IDD in northeastern Thailand, studies showed people in this region continue to have the lowest median urinary iodine (UI) excretion and Intelligence Quotient scores. We conducted a cross sectional study of median urinary iodine excretion among primary school children in suburban Khon Kaen Province, in northeastern Thailand, during December 2012 to evaluate the current status of IDD in this population.

Prevalence of Congenital Heart Diseases in Patients with Orofacial Clefts: A Systematic Review.

Background: The reports on prevalence rates of congenital heart diseases (CHDs) in patients with orofacial clefts (OFCs) have varied widely.

Objective: To systematically review the prevalence rates of CHDs in patients with OFCs.

Material And Method: A computer search was conducted through the PubMed from 1950 to June 2015 using key words or search terms of congenital heart diseases, orofacial clefts, cleft lip/palate and prevalence.

Global Birth Prevalence of Orofacial Clefts: A Systematic Review.

Background: A birth prevalence of orofacial clefts (OFCs) worldwide has been documented to vary. However a systematic assessment is lacking.

Objective: To assess the evidence in the literature for the birth prevalence of OFCs.

Prevalence and type of associated syndromes in patients with cleft lip and cleft palate who received the treatment in Tawanchai Center until 4-5 years of age.

Background: Understanding the genetic etiologies of cleft lip and palate (CLP) is important for improved prevention, treatment, and prognosis for patients affected by CLP.

Objective: To report the prevalence and the type of associated syndromes in Northeastern Thai patients with CLP.

Material And Method: A retrospective study of123 cleft lip/palate children aged 4-5 years was carried out at the Tawanchai Cleft Centel; Khon Kaen University during the period from October to December 2011.

Enamel defect and gingival enlargement in pediatric patients with kidney disease at Srinagarind Hospital, Khon Kaen University, Thailand.

Background: Although many complications from kidney disease therapy can be prevented or effectively treated, oral health problems are nevertheless a consequence.

Objective: The objective of this study was to explore the prevalence of enamel defect and gingival enlargement in pediatric patients with kidney disease at Srinagarind Hospital, Khon Kaen University, Thailand.

Material And Method: This cross-sectional study was conducted between January and August 2013, at SrinagarindHospital, Khon Kaen University.

Treatment of 4-5 year old patients with cleft lip and cleft palate in Tawanchai Center: prevalence and type of associated malformations.

Background: Patients with cleft lip/palate may have other associated malformations but the reported prevalence and type of associated malformations varied between different studies.

Objective: To report the prevalence and the type of associated malformations in Northeastern Thai patients with cleft lip/palate.

Material And Method: A retrospective study of 123 cleft lip/palate patients aged 4-5 years was carried out at the Tawanchai Cleft Center, Khon Kaen University during the periodfrom October to December 2011.

The rising incidence of type 1 diabetes in the northeastern part of Thailand.

Objective: To determine the incidence of T1DM in children under 15 years in 19 provinces in northeast Thailand.

Material And Method: Data of new cases of T1DM during 10 years between 1996 and 2005 were collected retrospectively by a mail survey from 275 hospitals in northeast Thailand.

Results: Three hundred forty cases, 134 (39.

Prevalence of type II diabetes and metabolic syndrome among overweight school children in Khon Kaen, Thailand.

Background: Childhood obesity has been accompanied by an increase in the prevalence of type 2 diabetes mellitus (T2DM) and metabolic syndrome (MetS) among children and adolescents worldwide.

Objective: To determine the prevalence of T2DM and MetS among overweight children and adolescents in Khon Kaen province, Northeast Thailand.

Material And Method: A cross-sectional, prospective pilot study was performed in school children between 10 and 15 years of age.

Acute suppurative thyroiditis with thyrotoxicosis.

Background: Acute suppurative thyroiditis (AST) is a rare condition in children, and most children with AST usually have normal thyroid function.

Objective: To report a case of thyrotoxicosis complicating AST in a child.

Case Report: A 6-year-old boy with AST presented with the unusual clinical features of severe thyrotoxicosis.

Evolution of valve damage in Sydenham's chorea during recurrence of rheumatic fever.

Background: The evolution of valve damage during a recurrence, in a patient who did not have apparent carditis in the initial attack of Sydenham's chorea, has been a subject of debate.

Methods: Thirty-six patients with an initial episode of acute rheumatic fever and Sydenham's chorea (3 patients with subclinical mitral regurgitation) were followed up prospectively for 5 years. Clinical examinations and transthoracic color Doppler echocardiography were done for each patient at initial attacks of Sydenham's chorea and at recurrences of rheumatic fever.

Epidemiologic study of Kawasaki disease and cases resistant to IVIG therapy in Thailand.

The incidence of Kawasaki disease (KD) in Thailand has never been studied before. We reviewed the data from the National Registry of Thai Children who had KD between 1998-2002 to evaluate the incidence of KD and cases resistant to treatment with intravenous immunoglobulin (IVIG). Resistance to IVIG was defined as remaining febrile at least 48 hours after initial IVIG therapy.

Aortoesophageal fistula: a life-threatening cause of upper gastrointestinal hemorrhage in double aortic arch, a case report.

The authors present the case of a 2-month-old infant with double aortic arch that developed massive bright red upper gastrointestinal hemorrhage from aortoesophageal fistula (AEF) after prolonged endotracheal and nasogastric intubation. Emergency thoracotomy with AEF and double aortic arch repaired were done successfully under cardiopulmonary bypass. Due to tracheomalacia and left phrenic nerve injury, tracheal extubation could not be done until 1 month after correction of the vascular ring.

Kawasaki disease in central area of Northeast Thailand.

Kawasaki disease (KD) is a leading cause of acquired heart disease of childhood. The authors retrospectively reviewed cases of KD in major referral centers of central Northeast Thailand from July 1991 to June 2003. Seventy-three episodes occurring in 72 patients were diagnosed with KD by the American Heart Association criteria with a mean age of presentation of 27 +/- 19 months.

The relationship of carditis to the initial attack of Sydenham's chorea.

Background: The natural history of valvular regurgitation detected by echocardiography in Sydenham's chorea has been lacking.

Methods: Clinical assessment and transthoracic color Doppler echocardiography were independently performed for each patient with an initial attack of Sydenham's chorea and also for each normal control (Khon Kaen University, Thailand; 1991-2001) at the time of their presentations. Serial clinical examinations and echocardiography were done for each patient at 1- and at 5-year follow-up.