Histological and immunohistochemical features of the placenta associated with COVID-19: a systematic review and meta-analysis.

Objective: Aim: To make a systematic review and meta-analysis of published data on the study of histological and immunohistochemical features of the placenta in women who had acute coronavirus infection associated with SARS-CoV-2 ("Covid" placentas) during pregnancy.

Patients And Methods: Materials and Methods: The search for literature data is based on the PRISMA methodology); the MEDLINE database (PubMed®) was searched using Medical Subject Headings terms from January 2020 to July 2023. The project was registered in the Open Sience Frame (Project Identifier: DOI 10.

CLINICAL AND EPIDEMIOLOGICAL FEATURES OF COVID-19 COURSE IN PREGNANT WOMEN.

Numerous studies have been devoted to the problem of the incidence of COVID-19 in pregnant women, but there is no sufficient evidence base to formulate specific recommendations for the management of pregnancy, prevention of perinatal complications and possible vertical transmission of the disease. The objective - to summarize clinical and epidemiological features of COVID-19 course and outcomes of labor in pregnant women in the Odessa region (Ukraine). 218 case histories of pregnancy and childbirth of women hospitalized to the specialized hospital base "Maternity hospital No.

[THE EFFICIENCY OF THERAPY WITH VITAMIN D METABOLITES OF STRUCTURAL AND FUNCTIONAL CHANGES IN THE BONE TISSUE IN WOMEN WITH ARTERIAL HYPERTENSION, OBESITY AND DEFICIENCY VITAMIN D].

The aim of work was to evaluate the efficacy of combination therapy with vitamin D metabolites on mineral bone density and markers of bone remodeling in postmenopausal women with arterial hypertension, obesity and vitamin D deficiency working in adverse environmental conditions. We examined 95 women aged from 48 to 60 years, 79 people (main group) had arterial hypertension, obesity and deficiency vitamin D and worked in adverse conditions of production, 16 were healthy women. The main group depending on the conducted treatment were divided into 3 groups: А group - received standard antihypertensive therapy, Cholecalciferol and Alfacalcidol; group B - standard antihypertensive therapy and Cholecalciferol; group C - standard antihypertensive therapy.

The analysis of methylation of DNA promoter of SFRP2 gene in patients with hyperplastic processes of the endometrium.

Unlabelled: The hyperplastic processes of the endometrium can arise not only against the background of excessive influence of estrogen, but also against the background of epigenetic damages that affect apoptosis, cell proliferation, differentiation, and adhesion, and DNA reparation. The aim of our study was to investigate and analyze the status of methylation of the promoter of SFRP2 gene in patients with hyperplastic processes of the endometrium.

Materials And Methods: The study groups were the following: I - patients with endometrial hyperplasia (EH, n = 9); II - patients with endometrial intraepithelial neoplasia (EIN, n = 10), III - control groups: 1) with endometrial cancer (EC, n = 4), and 2) healthy women (n = 4).