Comparison of Keratoconus Specific to Standard IOL Formulas in Patients With Keratoconus Undergoing Cataract Surgery.

Purpose: To assess the performance of multiple intraocular lens (IOL) formulas in eyes with keratoconus.

Methods: Eyes with stable keratoconus scheduled for cataract surgery with biometry measurements on the Lenstar LS900 (Haag-Streit) were included. Prediction errors were calculated using 11 different formulas, including two with keratoconus modifiers.

Epidemiologic Differences and Management of Eyelid Lesions in the Pediatric Population.

Purpose: To report the relative incidence of excised pediatric eyelid lesions and describe the correlation between the clinical and pathology diagnosis.

Methods: This was a retrospective analysis of 137 consecutive pathology-confirmed eyelid lesions excised at a U.S.

From education to action: Development and evaluation of a student-directed service learning program.

Purpose: Service learning consists of service activities that respond to community-identified concerns, active learning about the population being served, and self-reflecting on the experience. The Service Learning Program (SLP) is a novel, student-led, longitudinal volunteering experience designed to address social determinants of health (SDOH) education in the undergraduate medical school curriculum. In this program, medical students complete requirements in three domains of service, education, and self-reflection over the span of one academic year.

Intent-to-treat survival in liver transplantation has not improved in 3 decades due to donor shortage relative to waitlist growth.

Background: Liver Transplantation has advanced over the past 3 decades, with 1-year survival rates improving 25%. Survival rates for those transplanted has increased to remarkable levels, but survival from the time of listing may not be as revolutionary.

Methods: Kaplan-Meier with log-rank test as well as Cox regression analysis was used to retrospectively analyze 211 610 adults listed for LT and 116 299 adult transplant recipients from 1987 to 2016.

Prediction of Kidney Allograft Discard Before Procurement: The Kidney Discard Risk Index.

Objectives: There is an 18.9% discard rate among kidney allografts. Here, we aimed to determine predictors of kidney discard and construct an index to identify high-probability discard kidney allografts prior to procurement.

Pediatric discard risk index for predicting pediatric liver allograft discard.

Background: Of the 600 pediatric candidates added to the liver waiting list annually, 100 will remain waiting while over 100 liver allografts are discarded, often for subjective reasons.

Methods: We created a risk index to predict discard to better optimize donor supply. We used the UNOS database to retrospectively analyze 17 367 deceased donors (≤18 years old) through univariate and multivariate logistic regression models.

A learning curve in using orphan liver allografts for transplantation.

Given the critical shortage of donor livers, marginal liver allografts have potential to increase donor supply. We investigate trends and long-term outcomes of liver transplant using national share allografts transplanted after rejection at the local and regional levels. We studied a cohort of 75 050 candidates listed in the Organ Procurement and Transplantation Network for liver transplantation between 2002 and 2016.

Clinical providers' experiences with returning results from genomic sequencing: an interview study.

Background: Current medical practice includes the application of genomic sequencing (GS) in clinical and research settings. Despite expanded use of this technology, the process of disclosure of genomic results to patients and research participants has not been thoroughly examined and there are no established best practices.

Methods: We conducted semi-structured interviews with 21 genetic and non-genetic clinicians returning results of GS as part of the NIH funded Clinical Sequencing Exploratory Research (CSER) Consortium projects.

Bioscouring of cotton using lipase from marine bacteria Bacillus sonorensis.

Bioscouring refers to the enzymatic removal of impurities from cotton fabric, which imparts it with improved hydrophilicity for further wet processes. In the present study, the efficacy of lipase from newly isolated marine bacteria Bacillus sonorensis isolated from marine clams Paphia malabarica collected from Kalbadevi estuary, Mumbai, India, has been evaluated for scouring of cotton fabric and compared with conventional alkaline scouring of cotton. As a scouring agent for cotton fabrics, the lipase from B.

Characterization, kinetic, and thermodynamic studies of marine pectinase from Bacillus subtilis.

Characterization, kinetic and thermodynamic parameters of purified pectinase from Bacillus subtilis, isolated from a marine sediment sample collected from Chinchani beach at Tarapore, India, were studied. Marine pectinase produced under submerged growth conditions was purified by ammonium sulfate precipitation followed by gel filtration chromatography using DEAE cellulose. Partial characterization of the marine pectinase was carried out in terms of effect of pH, temperature, substrate concentration, and metal ions.

A change in humidification system can eliminate endotracheal tube occlusion.

Purpose: Inadequate airway humidification can result in endotracheal tube occlusion. There is evidence that heat and moisture exchangers (HMEs) are more prone to endotracheal tube occlusion than heated humidifiers (HHs) that contain a heated wire circuit. We aimed to compare the incidence of endotracheal tube occlusion while introducing a new dual-heated wire circuit HH in place of an established hydrophobic HME.