Publications by authors named "Manash Barthakur"

Gold nanoparticles are one of the widely used metallic nanoparticle having unique surface plasmon characteristic, offers major utility in biomedical and therapeutic fields. However, chemically synthesized nanoparticle creates toxicity in the living organisms and contradicts the eco-friendly and cost-effective nature. So, developing greener synthetic route for synthesis of gold nanoparticle using natural materials is an enthralling field of research for its effectiveness in synthesizing eco-friendly, non-toxic materials.

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Tea is a natural beverage made from the tender leaves of the tea plant ( Kuntze). Being of a perennial and monoculture nature in terms of its cultivation system, it provides a stable micro-climate for various insect pests, which cause substantial loss of crop. With the escalating cost of insect pest management and increasing concern about the adverse effects of the pesticide residues in manufactured tea, there is an urgent need to explore other avenues for pest management strategies.

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Article Synopsis
  • Alzheimer's disease (AD) is a permanent memory disorder linked to harmful processes in the brain, particularly involving amyloid beta (Aβ) that causes cell damage through oxidative stress and mitochondrial issues.
  • A new compound called benzimidazole functionalized polyfluorene (PFBZ) has been developed that selectively targets and binds to the toxic Aβ, effectively protecting mouse brains from amyloid-induced damage by preventing toxicity and oxidative stress.
  • PFBZ demonstrates unique benefits, including high biocompatibility, specific targeting of amyloid-related damage, and the ability to cross the blood-brain barrier, offering promise as a nanodrug for treating neurotoxicity associated with Alzheimer's disease.
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