Publications by authors named "Manar Salah"
Article Synopsis
- Hepatocellular carcinoma (HCC) is the most common liver cancer, often caused by chronic hepatitis and cirrhosis, with this study aiming to examine the genomic characteristics of HCC in Egyptian patients through whole exome sequencing.
- Whole exome sequencing was performed on 13 HCC patients who underwent surgery, revealing specific mutational signatures and a set of highly mutated genes associated with HCC, including notable mutations in APOB and RP1L1 across multiple studies.
- The findings confirmed previously established patterns in HCC genetics, identifying critical signaling pathways and potential clinical targets, highlighting the importance of these mutations for future research and therapy development.
Background: Bile stones are associated with numerous complications in liver transplant recipients. Endoscopic retrograde cholangiopancreatography (ERCP) has been proven to be safe and highly effective in dealing with most post-transplant biliary complications.
Objective: The objective of this study was to identify the possible risk factors for bile stone formation on top of biliary stricture, the effects of stones on graft outcomes, and their management.
Background: Patients who undergo living donor liver transplantation (LDLT) may suffer complications that require intensive care unit (ICU) readmission.
Aim: To identify the incidence, causes, and outcomes of ICU readmission after LDLT.
Methods: A retrospective cohort study was conducted on patients who underwent LDLT.
Background: Biliary complications (BCs) after liver transplantation (LT) remain a considerable cause of morbidity, mortality, increased cost, and graft loss.
Aim: To investigate the impact of BCs on chronic graft rejection, graft failure and mortality.
Methods: From 2011 to 2016, 215 adult recipients underwent right-lobe living-donor liver transplantation (RT-LDLT) at our centre.
Background: Despite significant advancements in liver transplantation (LT) surgical procedures and perioperative care, post-LT biliary complications (BCs) remain a significant source of morbidity, mortality, and graft failure. In addition, data are conflicting regarding the health-related quality of life (HRQoL) of LT recipients. Thus, the success of LT should be considered in terms of both the survival and recovery of HRQoL.
View Article and Find Full Text PDFBackground And Study Aims: Although unclear, the pathophysiology of irritable bowel syndrome (IBS) is considered to be multifactorial. Recent studies have suggested that IBS is a low-grade inflammatory bowel disease (IBD) with high faecal calprotectin (FC) levels. Rifaximin is a potential therapeutic agent for IBS with diarrhoea (IBS-D) due to its ability to decrease FC levels.
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