Integrating computational insights in gold nanoparticle-mediated drug delivery: enhancing efficacy and precision.

Gold nanoparticles (AuNPs) have emerged as a versatile platform in biomedical applications, particularly in drug delivery, cancer therapy, and diagnostics, due to their unique physicochemical properties. This review focuses on the integration of computational methods and artificial intelligence (AI) with nanotechnology to optimize AuNP-based therapies. Computational modeling is essential for understanding the interactions between AuNPs and biological molecules, guiding nanoparticle design for improved targeting, stability, and therapeutic efficacy.

Awareness of Obesity and Weight Loss Management Among Adults in the Asir Region, Saudi Arabia.

Obesity, a chronic disease marked by excessive fat accumulation and a body mass index (BMI) of 30 kg/m² or more, has become a major global health issue, affecting many adults worldwide and particularly prevalent in developed nations and Saudi Arabia. The condition can be caused by genetic, metabolic, and lifestyle factors. Understanding its awareness is imperative in designing effective health interventions.

Social Media Use and Sleep Quality Among Secondary School Students in Aseer Region: A Cross-Sectional Study.

Background: Use of different social media platforms has increased radically over the past decade, emerging as an important part of adolescents and young people's everyday life. This might exert potential adverse effects on sleep quality and daytime performance of young adults.

Aim Of Study: To assess the relation between use of social media platforms and sleep quality among public secondary school students.

Gender-Related Microaggressions in Orthopedic Surgery: A Comprehensive Survey of Women Orthopedists and Implications for Progress, Saudi Arabia.

Background: Microaggressions are subtle and often unintentional acts that can be verbal, nonverbal, or environmental, and they convey negative messages to individuals belonging to marginalized social groups. This study aims to determine the prevalence of microaggressions experienced by female Saudi orthopaedic surgeons.

Methods: This cross-sectional study was conducted online and targeted female in orthopedic surgery across different regions of the Kingdom of Saudi Arabia.

Health-Related Quality of Life in Individuals with Crohn's Disease: A Sample from Saudi Arabia.

Background: This study was conducted to compare health-related quality of life between adults with Crohn's disease (CD) and healthy controls (CONs).

Methods: A comparative cross-sectional study was conducted on adults with CD and CONs in Saudi Arabia (aged 18-60 years). Sociodemographic data (area of residence, education level, employment, and marital status) were collected from both groups, as well as additional information including disease onset, treatment, and symptomology from the CD group.

Pattern of childhood brucellosis in Najran, south Saudi Arabia in 2013-2017.

Background: With more than 500,000 new cases annually, human brucellosis is the commonest zoonotic disease worldwide. In some endemic countries, its prevalence is more than 10 per 100,000 population.

Objective: The aim of this study was to determine the magnitude of the problem and the clinical features, laboratory findings, treatment given and complications seen in children with brucellosis in Najran City, Kingdom of Saudi Arabia.