Publications by authors named "Manar Ali"

Background: Roux-en-Y gastric bypass (RYGB) is widely regarded as a cornerstone intervention for individuals afflicted with metabolic syndromes and severe obesity. However, one anastomosis gastric bypass (OAGB) emerged after RYGB as a more straightforward and less technically demanding operation. This systematic review and meta-analysis aims to compare both procedures and update the currently existing evidence.

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Ethnopharmacological Relevance: Sphagneticola trilobata was traditionally used to alleviate wounds using topical plant preparations. The precise mechanism of the plant responsible for its wound healing effect are still unclear. Although the plant was reported to be cytotoxic, there is a lack of reported data regarding its cytotoxic impact on skin cancer.

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Traffic flow prediction is a pivotal element in Intelligent Transportation Systems (ITSs) that provides significant opportunities for real-world applications. Capturing complex and dynamic spatio-temporal patterns within traffic data remains a significant challenge for traffic flow prediction. Different approaches to effectively modeling complex spatio-temporal correlations within traffic data have been proposed.

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Background: It has been observed that 5-8% of primary bariatric procedures result in inadequate treatment response, necessitating the need for revisional surgery. In this systematic review and meta-analysis, we aim to compare the effectiveness of single anastomosis duodeno-ileal bypass (SADI) and one anastomosis gastric bypass (OAGB) in addressing weight recurrence following sleeve gastrectomy.

Methods: We systematically searched PubMed, Scopus, Web of Science, and Cochrane Central Register of Controlled Trials databases.

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Ulcerative colitis (UC) is a chronic relapsing intestinal inflammation that is becoming of increasing incidence worldwide and has insufficient treatment. Therefore, finding effective therapies remains a priority. A dextran sodium sulfate colitis model was established to elucidate colonic layers alterations and compare adipose mesenchymal stem cell-derived microvesicles (MSC-MVs) versus infliximab (IFX) efficacy through biochemical, light, and electron microscope studies.

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Infective endocarditis (IE) is a serious cardiac infection of the endocardium, native and prosthetic valves, or cardiac device. In this case study, we report a case of an immunocompetent patient with severe aortic valve endocarditis. A 54-year-old female presented to the emergency department with progressive shortness of breath, chest pain, palpitations, and cough for a period of 20 days.

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Article Synopsis
  • Microneedling is recognized as a safe and effective treatment for post-acne scars, particularly atrophic scars.
  • This study compared the effects of microneedling combined with topical insulin versus a placebo (saline) on acne scars in 21 patients using a split face method over 4 sessions.
  • Both treatments resulted in significant improvement in scar appearance, but there was no significant difference in effectiveness or side effects between the insulin and placebo groups, indicating the potential for further exploration of insulin in scar treatment.
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Background: Metformin has been shown to have antitumor activity in different tumor types. In DLBCL (Diffuse large B cell lymphoma), using metformin with front-line chemotherapy & immunotherapy resulted in improved clinical outcomes.

Objectives: To assess the effectiveness of incorporating metformin into the standard initial treatment regimen of R-CHOP for patients with DLBCL.

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Article Synopsis
  • - Sarcoidosis is an unknown cause, multi-organ disease primarily impacting the lungs, and Darier-Roussy subcutaneous sarcoidosis is a rare skin manifestation that can mimic abscesses.
  • - A case study involved a 65-year-old female with multiple deep skin lesions, inflammation, and joint pain, initially treated as abscesses but unresponsive to antibiotics.
  • - Diagnosis was confirmed through a CT scan revealing lymphadenopathy and a skin biopsy showing sarcoidosis traits; treatment included hydroxychloroquine and tapering prednisone, highlighting the need to consider subcutaneous sarcoidosis in similar cases.
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Breast cancer (BC) is the most common malignancy in female individuals worldwide. It constitutes about 38.8% of all malignant tumors among Egyptian female individuals.

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Despite its wide range of application, cyclophosphamide (CP) exhibits a wide range of adverse effects including reproductive toxicity. The emerging field of zinc oxide nanoparticles (ZnO NPs) therapy may provide a new hope for prevention of CP induced gonadal toxicity. Herein, we aim to investigate the possible role of ZnO NPs as a new strategy to protect against CP induced testicular injury.

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