Background: Catheter-directed interventions (CDIs) for pulmonary embolism (PE) continue to evolve. However, due to the paucity of data, their use has been limited in patients with underlying kidney disease.
Methods: The National Readmission Database (2016-2020) was utilized to identify intermediate to high-risk PE (IHR-PE) patients requiring CDI (thrombectomy, thrombolysis, and ultrasound-assisted thrombolysis).
In the title compound, CHNO the pyrrolidine ring is almost planar and subtends a dihedral angle of 85.77 (7)° with the pendant phenyl ring. An intra-molecular N-H⋯O hydrogen bond generates an (6) loop.
View Article and Find Full Text PDFThe title di-thio-carbazate imine, CHNOS, was obtained from the condensation reaction of -methyl-dithio-carbazate (SMDTC) and 5-methyl-isatin. It shows a configuration about the imine C=N bond, which is associated with an intra-molecular N-H⋯O hydrogen bond that closes an (6) ring. In the crystal, inversion dimers linked by pairwise N-H⋯O hydrogen bonds generate (8) loops.
View Article and Find Full Text PDFThe title racemic oxopyrrolidine compound, CHNO, contains three stereogenic centres and crystallizes with two mol-ecules in the asymmetric unit. The five-membered pyrrolidine rings in both mol-ecules exhibit envelope conformations. The -ethyl group of one of the mol-ecules is disordered over two sets of sites in a 0.
View Article and Find Full Text PDFPurpose: This study introduces GraFMRI, a novel framework designed to address the challenges of reconstructing high-quality MRI images from undersampled k-space data. Traditional methods often suffer from noise amplification and loss of structural detail, leading to suboptimal image quality. GraFMRI leverages Graph Neural Networks (GNNs) to transform multi-modal MRI data (T1, T2, PD) into a graph-based representation, enabling the model to capture intricate spatial relationships and inter-modality dependencies.
View Article and Find Full Text PDFEnsuring diversity within the healthcare sector is essential for improving team dynamics and ultimately patient outcomes. Diversity among medical students is fundamental to embody this philosophy. With the demand for diversity in the admissions process gaining traction, the authors expanded this conversation to the editorial boards (EBs) of Medical Student Journals (MSJs).
View Article and Find Full Text PDFThe title compound, CHBrNOS, a brominated di-thio-carbazate imine deriv-ative, was obtained from the condensation reaction of -methyl-dithio-carbazate (SMDTC) and 5-bromo-isatin. The essentially planar mol-ecule exhibits a configuration, with the di-thio-carbazate and 5-bromo-isatin fragments located on the same sides of the C=N azomethine bond, which allows for the formation of an intra-molecular N-H⋯O (b = bromo-isatin) hydrogen bond generating an (6) ring motif. In the crystal, adjacent mol-ecules are linked by pairs of N-H⋯O hydrogen bonds, forming dimers characterized by an (8) loop motif.
View Article and Find Full Text PDFBackground: Occupational diseases are one of the most important health problems related to employment However, in Malaysia, there are few epidemiological studies discussing these issues, especially among workers in the industry. For that, this study aimed to screen workers from high-risk industrial sectors, identify hazards in the workplace and recommend improvement measures in the workplace to prevent occupational diseases.
Methods And Analysis: This is a 3-year project in which a survey of 100 000 workers from all 13 states in Malaysia will be conducted using a web-based screening tool that is comprised of two parts: occupational disease screening tool and hazard identification, risk assessment and risk control method.
Ann Med Surg (Lond)
August 2024
Myeloproliferative neoplasms (MPNs) occur due to the abnormal proliferation of one or more terminal myeloid cell lines in peripheral blood. Subjects suffering from MPNs display a high burden of cardiovascular risk factors, and thrombotic events are often the cause of death in this population of patients. Herein, we provide a brief overview of dyslipidemia and metabolic syndrome and their epidemiology in MPNs and examine the common molecular mechanisms between dyslipidemia, metabolic syndrome, and MPNs, with a special focus on cardiovascular risk, atherosclerosis, and thrombotic events.
View Article and Find Full Text PDFBackground: Arboviruses are RNA viruses and some have the potential to cause neuroinvasive disease and are a growing threat to global health.
Objectives: Our objective is to identify and map all aspects of arbovirus neuroinvasive disease, clarify key concepts, and identify gaps within our knowledge with appropriate future directions related to the improvement of global health.
Methods: : A scoping review of the literature was conducted using PubMed, Scopus, ScienceDirect, and Hinari.
Cardiovascular diseases (CVDs) are the major cause of death among Malaysians. Reduction of salt intake in populations is one of the most cost-effective strategies in the prevention of CVDs. It is very feasible as it requires low cost for implementation and yet could produce a positive impact on health.
View Article and Find Full Text PDFThe title compound, CHFNOS, a fluorinated di-thio-carbazate imine derivative, was synthesized by the one-pot, multi-component condensation reaction of hydrazine hydrate, carbon di-sulfide, 4-fluoro-benzyl chloride and isatin. The compound demonstrates near-planarity across much of the mol-ecule in the solid state and a configuration for the azomethine C=N bond. The form is further stabilized by the presence of an intra-molecular N-H⋯O hydrogen bond.
View Article and Find Full Text PDFThe title compound, CHNOS was obtained from the condensation reaction of -benzyl-dithio-carbazate and 5-methyl-isatin. In the solid-state, the mol-ecule adopts a configuration with the 5-methyl-isatin and di-thio-carbazate groups located on the same side of the C=N bond, involving an intra-molecular N-H⋯O hydrogen bond.
View Article and Find Full Text PDFUnusual presentations and uncommon clinical manifestations of Monkeypox (Mpox) in the current outbreak highlight the need to focus on cardiac symptoms of the virus. Owing to limited discussion regarding cardiac involvement in recent cases of Mpox, we conducted a scoping review to determine the range of existing research and provide a descriptive overview of the current literature on these manifestations. This review was conducted using a previously developed six-stage methodological approach and keeping in view the Preferred Reporting Items for Systematic Reviews and Meta-analyses extension for Scoping Reviews (PRISMA-ScR).
View Article and Find Full Text PDFThe title compound, CHNO, a new derivative of isoxazole, has been synthesized and structurally characterized. The crystal structure shows the mol-ecule to be almost planar (r.m.
View Article and Find Full Text PDFPurpose Of The Article: As editorial boards (EBs) of medical education journals (MEJs) hold substantial control over framing current medical education scholarship, we aimed to evaluate representation of women as well as geographic and socioeconomic diversity on EBs of these journals.
Materials And Methods: In our cross-sectional study, Composite Editorial Board Diversity Score (CEBDS) was used to evaluate diversity at gender, geographic region, and country income level. Websites of MEJs were screened for relevant information.
Unlabelled: Journals have been described as "duty bearers" of upholding fundamental ethical principles that are essential for maintaining the ethical integrity of newly generated and disseminated knowledge. To play our part, we evaluated diversity and inclusion in the leadership and management of global and international health journals. We developed Journal Diversity Index (JDI) to measure three parameters of diversity and representation (gender, geographic, socioeconomic status).
View Article and Find Full Text PDFNeurotropic viruses are a threat to human populations due to ongoing zoonosis. A wide array of neurological manifestations can occur most often including parkinsonism, encephalitis/encephalopathy, flaccid myelitis, and Guillain-Barré syndrome. Neuroinvasion occurs through: transneural transmission, blood brain barrier (BBB) dysfunction, and 'trojan horse' mechanism or infected immune cell trafficking into the central nervous system (CNS).
View Article and Find Full Text PDFThis research examines the impact of self-polymerized polydopamine (PDA) coating on the mechanical properties and microstructural behavior of polylactic acid (PLA)/kenaf fiber (KF) composites in fused deposition modeling (FDM). A biodegradable FDM model of natural fiber-reinforced composite (NFRC) filaments, coated with dopamine and reinforced with 5 to 20 wt.% bast kenaf fibers, was developed for 3D printing applications.
View Article and Find Full Text PDF