Publications by authors named "Manali Ranade"
Article Synopsis
- CDKN2A/B homozygous deletion is a key characteristic of grade 4 IDH-mutant astrocytic tumors, making it important to understand its clinical implications.
- A study found that 71% of lower-grade tumors and 90% of grade 4 tumors exhibited this deletion, with reliable results from two interpretation methods.
- The deletion correlated with factors such as a lower MIB-1 labeling index, but no significant differences were seen in disease progression among the different histological grades, suggesting that while CDKN2A/B deletion is more common in higher grades, it does not significantly impact patient outcomes.
