Weight gain in gestational diabetes: the effect of treatment modality.

Objective: To evaluate treatment effectiveness (diet alone, insulin or glyburide) on maternal weight gain in gestational diabetes (GDM).

Methods: GDM patients were treated with diet alone, insulin or glyburide. Weight gain was stratified into: prior to GDM diagnosis, from diagnosis to delivery and total pregnancy weight gain.

Electrical pacemaker as a safe and feasible method for decreasing the uterine contractions of human preterm labor.

Aim: The aim of the study was to test the safety and feasibility of a system designed to decrease the uterine contractions of human preterm labor using a weak electrical current.

Methods: Patients in preterm labor had an electrode catheter placed in the posterior vaginal fornix and attached to an electrical pacemaker. Contraction intervals were determined during the 60-min study, in which minutes 0-20 was the preintervention control period (C1); 21-40 was the electrical intervention (EI), with a 10-s burst of current administered just before each expected contraction; and 41-60 was the postintervention control (C2).

Male-to-female gender ratio in fetuses with increased nuchal translucency.

Objective: To describe gender distribution in fetuses with increased nuchal translucency (NT) measurements.

Methods: All fetuses with mild (2.5-2.

First-trimester crown-rump length as a predictor of fetal LGA and SGA at term.

Objective: To determine whether first-trimester crown-rump length (CRL) is associated with birthweight extremes at term.

Methods: Included in this study were all term, small for gestational age (SGA), and large for gestational age (LGA) neonates with no other obstetric complications and no abnormal outcomes of pregnancy. CRL at 12.

Hypoglycemia in glyburide-treated gestational diabetes: is it dose-dependent?

Objective: To estimate whether there is a relationship between glyburide dose and the rate of hypoglycemic episodes in women with gestational diabetes mellitus (GDM).

Methods: We studied 674 women with GDM who were treated with glyburide and diagnosed from 2000 to 2009. Glucose data were downloaded from memory-based meters at each visit and analyzed to estimate the incidence of recorded episodes of hypoglycemia and the association with concurrent dose of glyburide therapy (2.