Publications by authors named "Manal T El-Sayed"

Ochratoxin A (OTA) is a mycotoxin produced by Aspergillus spp. and Penicillium spp. that causes a threat to food safety and human health.

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Aims: Contamination with heavy metal (HM) is a severe environmental issue. Therefore, there is a pressing need to create environmentally safe and cost-effective HM bioremediation approaches.

Methods And Results: Three iron-tolerant fungal strains were isolated from sewage-irrigated soils, molecularly identified and deposited in the GenBank as Aspergillus flavus MT639638, A.

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Mycotoxigenic fungi have attracted special attention due to their threat to food security and toxicity to human health. Aqueous extract of Roscoe was used as reducing and capping agent for the synthesis of silver (AgNPs), copper (CuNPs), and zinc oxide (ZnONPs) nanoparticles. UV-Visible spectra of the AgNPs, CuNPs, and ZnONPs showed absorption peaks at λ 416 nm, 472 nm, and 372 nm, respectively.

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Evaluating the mechanism of tolerance and biotransformation Zn(II) ions by based on the different physiological was the objective of this work. The physical properties of synthesized ZnONPs was determined by UV-spectroscopy, transmission electron microscope, and X-ray powder diffraction. The structural and anatomical changes of in response to Zn(II) was examined by TEM and SEM.

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Endophytic fungi have been considered as a repertoire for bioactive secondary metabolites with potential application in medicine, agriculture and food industry. The biosynthetic pathways by fungal endophytes raise the argument of acquisition of these machineries of such complex metabolites from the plant host. Diterpenoids "Taxol" is the most effective anticancer drug with highest annual sale, since its discovery in 1970 from the Pacific yew tree, .

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Silver ions discharged from various industries, are potentially toxic to living organisms at low concentrations, thus, there is an increasing need for development of an eco-friendly and cost-effective approach for its bioremediation. Filamentous fungi especially, displayed a strong resistance to copper and cadmium ions as revealed from our previous study (El-Sayed 2014), however, the mechanisms of silver resistance by this fungus has not been resolved yet. Thus, this study was an extension to our previous work, to elucidate the mechanism of silver ions resistance and biotransformation by .

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Antibiotic resistance by pathogenic bacteria and fungi is one of the most serious global public health problems in the 21 century, directly affecting human health and lifestyle. and with strong resistance to the common antibiotics have been isolated from Intensive Care Unit patients at Zagazig Hospital. Thus, in this study we assessed the biocidal activity of nanoparticles of silver, copper and zinc synthesized by KJ 623702 against these multidrug resistant-bacteria.

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