Publications by authors named "Manabu Sugita"

Introduction: We retrospectively analyzed convulsive patient outcomes transported by a physician-staffed Helicopter Emergency Medical Service (doctor helicopter [DH]) using the keyword-triggered dispatch with data from the Japan DH Registry System (JDRS). Upon receiving an emergency call containing critical keywords, such as an ongoing convulsion at the firefighting central command room, immediate dispatch of the DH is requested, in addition to dispatching an ambulance. The keyword-triggered dispatch relied on data obtained from the JDRS.

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Objective: To evaluate the effect of emergency medicine training credentials and years of medical experience on various clinical parameters in emergency medicine practice.

Methods: A cross-sectional study was conducted at Juntendo University Nerima Hospital between 1 April 2019 and 31 March 2020. All patients who were transported by ambulance, were examined by emergency physicians, and underwent computed tomography (CT) or magnetic resonance imaging (MRI) in the emergency department were included.

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  • A 71-year-old woman experienced severe allergic reactions, including anaphylaxis, after receiving an injection of JOYCLU, highlighting potential risks associated with the treatment.
  • Although a basophil activation test (BAT) showed no positive findings, the case underscores the need for better testing methods and caution during JOYCLU administration, especially as OA cases increase.
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  • A 28-year-old woman with no serious health issues got really sick with dizziness and vomiting, leading to surgery for her brain after doctors found a problem with her blood vessels.* -
  • Later on, she developed a fever and was diagnosed with an infection caused by a germ called Corynebacterium striatum, which was affecting her heart's mitral valve.* -
  • After surgery to replace her damaged mitral valve, she was given medicine for 31 days and got better, leaving the hospital without any further problems.*
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  • A 76-year-old woman developed an iliopsoas abscess following an acute urinary tract infection, initially presenting with fatigue and difficulty moving.
  • Despite blood tests showing inflammation, the source was not clear until further imaging.
  • After CT-guided drainage of the abscess, she improved and was transferred to a rehabilitation hospital, marking this as the first documented case of such an infection after acute pyelonephritis.
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  • Viral hepatitis is a significant global health threat, leading to high mortality rates and liver complications from five different viruses: Hepatitis A, B, C, D, and E.
  • Despite some effective treatments, many patients still suffer due to gaps in healthcare and the need for more accessible therapies.
  • The World Health Organization's 2016 plan aims to eliminate viral hepatitis as a public health issue by 2030, emphasizing the need for safer, shorter treatments and better understanding of the disease's mechanisms.
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  • The study analyzed data from the Tokyo 2020 Games to understand why athletes were transferred to local medical facilities, focusing on 567 injuries and illnesses treated at on-site clinics.
  • During the Olympics, most athlete transfers were due to injuries (72.7%), with a small percentage requiring hospitalization for more than 7 days, while the Paralympics had a more balanced distribution with half of the cases being other illnesses.
  • This research highlights the significant volume and types of medical issues athletes faced, providing insights not previously recorded in earlier Olympic and Paralympic events.*
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  • The WHO recommends focusing on specific outcomes like oxygen use and mechanical ventilation to assess COVID-19 vaccine effectiveness (VE), especially post-Omicron, due to variability in hospitalization data.
  • A study in Japan examined VE among 2125 individuals during the Delta and early Omicron periods, finding that 2 doses provided strong protection during Delta, while 3 doses were effective during Omicron.
  • Results showed high VE for both variants, particularly for severe outcomes, highlighting the importance of booster shots in maintaining protection against severe COVID-19 disease.
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Background: Coronavirus disease 2019 (COVID-19)-associated invasive pulmonary aspergillosis presents a diagnostic challenge due to its non-specific clinical/ imaging features, as well as the fact that the proposed clinically diagnostic algorithms do not necessarily apply to COVID-19 patients. In addition, . is a rare cause of opportunistic life-threatening fungal infections.

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  • - Penoscrotal constriction devices can enhance erotic experiences but can lead to emergencies like penile strangulation, requiring urgent medical intervention to prevent lasting damage.
  • - A 47-year-old man with a history of HIV experienced severe pain and swelling after applying stainless steel rings to his penis and scrotum for sexual pleasure, leading to his hospitalization.
  • - Medical staff struggled to remove the constricting rings, ultimately using an electric grinder to cut them, successfully resolving the emergency, making this the first documented case in an HIV-positive patient.
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Background: In this study, we aimed to identify predictive factors for coronavirus disease 2019 (COVID-19) patients with complicated pneumonia and determine which COVID-19 patients should undergo computed tomography (CT) using classification and regression tree (CART) analysis.

Methods: This retrospective cross-sectional survey was conducted at a university hospital. We recruited patients diagnosed with COVID-19 between January 1 and December 31, 2020.

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A 44-year-old man with coronavirus disease 2019 (COVID-19) and nephrotic syndrome relapse was admitted to our intensive-care unit for respiratory failure. Despite receiving mechanical ventilation and immunomodulators, the patient experienced refractory hypoxemia, necessitating venovenous extracorporeal membrane oxygenation (VV-ECMO) therapy. Due to a worsening renal function, continuous hemodiafiltration was initiated.

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The European Society of Cardiology recommends the 0/1-hour algorithm for risk stratification of patients with suspected non-ST-elevation myocardial infarction as class I, level B; however, there are few reports on the long-term prognosis, resulting in a rule-out group. We aimed to determine whether implementation of the 0-hour/1-hour algorithm is safe and effective in emergency department (ED) patients with possible acute coronary syndrome (ACS) through a 1-year follow-up period. Our study analyzed the 1-year follow-up data from a prospective pre-post study of 1106 ED patients with possible ACS from 4 hospitals in Japan and Taiwan.

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Background: Dextromethorphan is a prevalent antitussive agent that can be easily obtained as an over-the-counter medication. There has been a growing number of reported cases of toxicity in recent years. Generally, there are numerous instances of mild symptoms, with only a limited number of reports of severe cases necessitating intensive care.

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  • A study analyzed injuries and illnesses among 11,420 athletes during the 2020 Tokyo Olympic Games, focusing on the period from July 21 to August 8, 2021.
  • A total of 567 athletes and 541 non-athletes were treated for a variety of injuries and illnesses, with marathons and race walking showing the highest incidence of issues.
  • The overall rates of injuries and heat-related illnesses were lower than expected, attributed to effective preparation and medical protocols at the venues, with no serious events reported.
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Introduction: Among the 43 venues of Tokyo 2020 Olympic Games (OG) and 33 venues of Paralympic Games (PG) were held, the heat island effect was highly expected to cause heat-related illnesses in the outdoor venues with maximum temperatures exceeding 35°C. However, the actual number of heat-related illness cases during the competition was lower than that was initially expected, and it was unclear under what conditions or environment-related heat illnesses occurred among athletes.

Object: To clarify the cause and factors contributing to the occurrence of heat-related illness among athletes participating in the Tokyo 2020 Olympic and Paralympic Games.

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Amebic liver abscesses (ALAs) are the most commonly encountered extraintestinal manifestation of human invasive amebiasis, which results from () spreading extraintestinally. Amebiasis can be complicated by liver abscess in 9% of cases, and ALAs led to almost 50000 fatalities worldwide in 2010. Although there have been fewer and fewer cases in the past several years, ALAs remain an important public health problem in endemic areas.

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A 78-year-old Japanese man was in a state of shock with skin flushing. Although he denied, his wife revealed his prescription disulfiram for alcoholism. Disulfiram-ethanol reaction, even though it is a rare cause of distributive shock, could be easily and quickly differentiated only based on accurate medical history and inspection.

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Background: Esophageal submucosal hematoma is a rare condition. Although the exact etiology remains uncertain, vessel fragility with external factors is believed to have led to submucosal bleeding and hematoma formation; the vessel was ruptured by a sudden increase in pressure due to nausea, and the hematoma was enlarged by antiplatelet or anticoagulant therapy. Serious conditions are rare, with a better prognosis.

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species are obligate aerobic, gram-positive, weak acid-fast, nonmotile bacilli. They are found in various environments, such as soil, water, sludge, and petroleum reservoir wastewater, and belong to the order . In 2016, there was a reclassification of species within the genus , merging the species () and .

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Acute myocardial infarction (AMI) in young patients is very rare, but the incidence has increased over years past at younger ages, likely due to the presence of multiple risk factors. We present the first known case of ST-elevation AMI (STEMI) in a young man. A 22-year-old Japanese man was transferred to our hospital due to suddenly occurred anterior chest pain.

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  • The study investigates the impact of a telemedicine system on reducing physical contact during the COVID-19 pandemic and its effects on nurses' mental health.
  • 100 nurses participated, and results showed that the system significantly decreased the number of daily patient visits and vital sign assessments needed.
  • Most nurses found the telemedicine system easy to use, felt it reduced their workload, provided relief, and effectively minimized the risk of infection, but their levels of distress and depression remained stable with or without the system.*
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is a genus comprising several species of opportunistic black yeasts, which belongs to Ascomycotina. It is a rare cause of fungal infections. However, infections are often chronic and recalcitrant, and while the number of cases is steadily increasing in both immunocompromised and immunocompetent people, detailed knowledge remains scarce regarding infection mechanisms, virulence factors, specific predisposing factors, risk factors, and host response.

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  • * Chronic heart failure (CHF) involves neurohumoral systems like the renin-angiotensin-aldosterone system, the sympathetic nervous system, and natriuretic peptides, which are important for understanding and treating the condition.
  • * Sacubitril/valsartan (SAC/VAL) is a new and effective treatment for chronic HF with reduced ejection fraction (HFrEF), improving patients' quality of life and reducing hospital stays, but more research is needed on its long-term safety and molecular effects.
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