Publications by authors named "Manabu Hibiya"

Article Synopsis
  • In Japan, doctor cars are specialized emergency medical vehicles staffed by physicians, designed to provide advanced trauma care before patients reach the hospital.
  • A nationwide study analyzed data from over 372,000 trauma patients to assess the impact of doctor cars compared to non-physician-staffed emergency services on survival rates.
  • The results indicate that patients treated by doctor cars have a significantly higher chance of survival in the hospital, suggesting that these units could enhance trauma care strategies in Japan.
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Objective: This study evaluated the changes in the status of glycemic control and lipid management in patients with diabetes under COVID-19 containment restrictions, in order to better understand the impacts of events causing lifestyle restrictions. Patient characteristics with worsened glycemic control were also assessed.

Methods: We conducted a retrospective and observational cohort study using the electronic health records of 5,169 patients with diabetes seeking medical care in two healthcare centers.

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Introduction: In Japan, evacuation at home is expected to increase in the future as a post-disaster evacuation type due to the pandemic, aging, and diverse disabilities of the population. However, more disaster-related indirect deaths occurred in homes than in evacuation centers after the 2011 Great East Japan Earthquake (GEJE). The health risks faced by evacuees at home have not been adequately discussed.

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Disaster-related deaths are of two types: direct and indirect. Preventable disaster-related deaths reported in the Great East Japan Earthquake (GEJE) included a large number of indirect deaths. This study aimed to investigate the data on disaster-related deaths in the GEJE in Ishinomaki City, Miyagi Prefecture, and to clarify the scope of disaster-related deaths to help future disaster preparedness.

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Aim: This study attempted to identify predictors of S-warfarin clearance (CL[S]) and to make a pharmacokinetic evaluation of genotype-based dosing algorithms in African-Americans.

Methods: Using plasma S-warfarin concentration (Cp[S]) at a steady state and eight SNPs previously shown to influence warfarin dose in African-Americans, CL(S) and its predictors were estimated by population pharmacokinetic analysis in 60 African-Americans. The time courses of Cp(S) following either the loading dose or maintenance dose were simulated using the population pharmacokinetic estimates.

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