Orbital decompression surgery and horse chestnut seed extract improved superior orbital vein blood flow in patients with thyroid-associated ophthalmopathy.

Aim: To evaluate the efficacy and safety of orbital decomposition (OD) surgery in combination with horse chestnut seed extract (HCSE), as compared to OD alone, in patients with thyroid-associated ophthalmopathy (TAO).

Methods: Sixty-two orbits from 62 TAO patients were randomly assigned to OD or OD+HCSE at 1:1 ratio (31 received OD alone, 31 received OD+HCSE). Forty-two orbits from 21 healthy subjects were used as controls.

MiRNA-21 promotes fibrosis in orbital fibroblasts from thyroid-associated ophthalmopathy.

Purpose: This study aimed to determine the role of miR-21 in orbital fibroblasts obtained from donors with thyroid-associated ophthalmopathy (TAO) and to elucidate the regulation of fibrosis by miR-21 in the pathological process of TAO.

Methods: The expression of miR-21 was investigated in orbital tissues from 26 donors with TAO and 10 donors without TAO. Human orbital fibroblasts were cultivated from TAO donors, and the role of miR-21 in orbital fibroblast proliferation, apoptosis, and differentiation was analyzed.

Meshed conjunctival incision technique: an efficient technique for contracted eye socket.

Objective: To present a surgical technique for socket reconstruction in cases in which forniceal shortening by scar has made it difficult to successfully wear an ocular prosthesis.

Methods: A retrospective analysis of 19 contracted eye sockets that underwent forniceal reconstruction with meshed conjunctival incision technique from 2009 to 2012. The technique included three steps: meshed conjunctival incision, lower forniceal reconstruction and upper fornix incision.

[Thickness of the retinal nerve fiber layer in unilateral amblyopic patients with high myopia in children].

Objective: To investigate the retina nerve fiber layer (RNFL) thickness in unilateral amblyopic patients with high myopia.

Methods: Twenty-three cases (23 eyes) with unilateral high myopia amblyopia were tested by GD(X) ECC with laser polarized light scans in the posterior pole of retina, to measure the relative RNFL thickness according to papilla optical as a center, 3.2 mm as the diameter of outer ring, 2.

[Clinical features and surgical treatment of congenital ocular muscle palsy characterized with double elevator dysfunction].

Objective: To investigate the clinical features of congenital ocular elevator muscle palsy and to evaluate the efficacy of surgical treatment.

Methods: Pre- and post-operative eye position, superior rectus muscle and inferior oblique muscle function, clinical features were examined and analyzed in 11 patients with congenital double elevator palsy of ocular muscles.

Results: When fixated with the nonparetic eye, ten of 11 patients showed hypotropia and pseudoblepharoptosis in the primary position; One of 11 patients fixated with the paretic eye and showed hypotropia in the primary position.

[A new probe for congenital nasolacrimal duct obstruction].

Objective: To investigate the therapeutic effect of a new probe for congenital nasolacrimal duct obstruction.

Methods: The probe was designed and manufactured by ourselves. We observed 158 cases (172 eyes) with congenital nasolacrimal duct obstruction and treated them with the probe 1-3 times.