Publications by authors named "Man Yin Chan"
Article Synopsis
- Researchers utilized a flow cytometry-based method to identify specific cell-surface markers that help separate different pancreatic cell types derived from human embryonic stem cells.
- The study found that pancreatic endoderm cells could be enriched using the markers CD142, while endocrine cells were enriched using CD200 and CD318.
- When transplanted into mice, the enriched endoderm cells developed into various functional pancreatic cells, including insulin-producing cells, proving their potential as pancreatic progenitors, whereas the polyhormonal endocrine cells mainly generated glucagon cells.
