Infrared Laser Pulses Excite Action Potentials in Primary Cortex Neurons In Vitro.

Infrared neural modulation (INM) has been well studied in the peripheral nervous system (PNS) for potential clinical applications. However, limited research has been conducted on the central nervous systems (CNS). In this study, we aimed at investigating the feasibility of using pulsed infrared (IR) laser with a wavelength of 1940 nm to excite network activity of cultivated rat cortex neurons.

Neuromuscular Electrical Stimulation with Kilohertz Frequency Alternating Current to Enhance Sensorimotor Cortical Excitability.

Enhancement of cortical excitability has been demonstrated to be beneficial for neural recovery of motor dysfunction, such as stroke and spinal cord injury. Neuromuscular electrical stimulation (NMES) has been widely used to evoke limb movements, resulting in the increasing cortical excitability. Due to the advantages of low skin impedance and less discomfort, an alternative NMES of kilohertz frequency alternating current (KFAC) has been proposed, and the effects of current parameters on evoked torque has been studied.

Optical stimulation of primary motor cortex with 980nm infrared neural stimulation.

To explore the penetration depth with short-wavelength infrared light, 980 nm pulse infrared light was used to stimulate the primary motor cortex of rat. The heating model was created to simulate the temperature distribution for 1875 nm and 980 nm infrared neural stimulation. Post-stimulus time histogram was used to observe the neural response induced by Infrared neural stimulation on primary motor cortex.

Pulsed 808-nm infrared laser stimulation of the auditory nerve in guinea pig cochlea.

Pulsed near-infrared radiation has been proposed as an alternative stimulus for auditory nerve stimulation and could be potentially used in the design of cochlear implant. Although the infrared with high absorption coefficient of water (i.e.