Publications by authors named "Man Koumba Soumahoro"
A multicountry evaluation of the Xpert MTB/RIF assay for the diagnosis of intrathoracic tuberculosis in children using alternative specimens (nasopharyngeal aspirate and stool): A prospective cohort study conducted in Madagascar, Ivory Coast and Cameroon (TB Kids project).
Int J Infect Dis
December 2024
Context: Tuberculosis (TB) diagnosis in children remains challenging due to the paucibacillary nature of specimens and the difficulty in obtaining suitable samples. The use of alternative samples like nasopharyngeal aspirate (NPA) and stools, alongside Xpert MTB/RIF testing, offers promising improvements.
Objective: This study aimed to assess the diagnostic performance of the Xpert MTB/RIF test on NPA and stool samples for detecting intrathoracic TB in children from Madagascar, Cameroon, and Ivory Coast.
Article Synopsis
- Whooping cough, caused by Bordetella pertussis and Bordetella parapertussis, is highly contagious and particularly dangerous for infants, with Africa having the highest incidence and mortality rates.
- A study conducted in Abidjan from April 2019 to July 2021 involved infants with coughs and their household contacts, finding a significant number of infections among both infants and family members.
- Results showed high circulation of pertussis in the community, emphasizing the need to address obstacles to accessing recommended booster vaccinations as suggested by the WHO.
Article Synopsis
- The study aimed to assess the effectiveness (sensitivity and specificity) of various diagnostic tests for childhood pulmonary tuberculosis (CPTB) using latent class analysis, given the lack of definitive reference standards.
- Conducted in the Ivory Coast, Madagascar, and Cameroon with 1,165 children suspected of having CPTB, multiple tests were evaluated, including smear microscopy, culture, and Xpert on different sample types.
- Results indicated that while smear microscopy was very specific, it had low sensitivity across all sample types; Xpert showed better sensitivity, particularly in gastric and nasopharyngeal aspirates, suggesting a potentially effective diagnostic strategy for CPTB.
Article Synopsis
- Human cysticercosis, caused by the parasite Taenia solium, is a significant health issue in specific regions of Latin America, Asia, and Sub-Saharan Africa, where diagnosing neurocysticercosis is challenging due to limited access to neuroimaging.
- Current serological tests like ELISA and Western blot are effective but costly, prompting the search for more affordable diagnostics, such as immunoassays using recombinant proteins.
- Researchers developed five recombinant proteins for testing, showing promise in diagnosing cysticercosis through ELISA, although performance needs enhancement; further studies are needed to assess their effectiveness in larger populations, particularly in remote areas with high epilepsy rates.
Background: Porcine cysticercosis is an endemic parasitic zoonosis in many developing countries. The objective of this study was to estimate the seroprevalence of porcine cysticercosis in traditional pig farms in the departments of Dabou, Aboisso and Agboville.
Methods: Blood samples were taken from pigs and analyzed by ELISA (IgG) and western blot.
Objective: This study was aimed at examining the vulnerability of Central Africa to the COVID-19 pandemic.
Methods: Demographic, health, and socio-economic indicators were used to describe the vulnerability. The study period was from December 31st, 2019 to May 31st, 2020 (i.
Cysticercosis is one of the main causes of secondary epilepsy in sub-Saharan Africa. To estimate the seroprevalence of cysticercosis among epileptic patients, we conducted a cross-sectional study of patients attending neurology consultation in Abidjan, Côte d'Ivoire. : Patients' socio-demographic and lifestyle data were collected as well as blood samples for serological testing using ELISA and Western blot based on IgG antibodies detection.
View Article and Find Full Text PDFArticle Synopsis
- A biobank is a facility that collects biological samples and their data for research, with ethical guidelines to ensure their proper use.
- A study conducted in southern Côte d'Ivoire revealed that 43.41% of laboratory staff were unaware of biobanking and only 48.78% understood its role effectively.
- The findings indicate a significant need for improved training among laboratory staff about biobanking, as misconceptions and a lack of knowledge were prevalent, particularly among technicians and PhD students.
Introduction The transmission of test results by laboratories and their receipt by health facilities are common tasks in the processing of medical information. Managing the flow of information generated by these tasks remains a challenge for these centers. We describe a new system that will allow for electronic management of the transmission of results.
View Article and Find Full Text PDFArticle Synopsis
- The study focuses on the emergence of Neisseria meningitidis W135 (NmW135) in Côte d'Ivoire and how it compares to the previously predominant NmA strain.
- Analysis of Nm samples collected between 2007 and 2012 revealed that NmW135 became more common, especially in northern health districts, while NmA samples have not been found since 2009.
- The findings suggest a significant shift in meningitis-causing bacteria in the region, emphasizing the need for improved surveillance to monitor bacterial trends and identify new serogroups.
Cysticercosis is caused by the larvae of the cestode Taenia solium. Few data are available on the prevalence of this disease in pigs and humans in West African countries. The aim of this study was to provide an overview of existing data concerning the spread of this parasitosis in the countries of the Economic Community of West African States (ECOWAS) on the basis of the literature published over the last five decades.
View Article and Find Full Text PDFBackground: This study was conducted to assess the impact of chikungunya on health costs during the epidemic that occurred on La Réunion in 2005-2006.
Methodology/principal Findings: From data collected from health agencies, the additional costs incurred by chikungunya in terms of consultations, drug consumption and absence from work were determined by a comparison with the expected costs outside the epidemic period. The cost of hospitalization was estimated from data provided by the national hospitalization database for short-term care by considering all hospital stays in which the ICD-10 code A92.
Background: Persistent symptoms, mainly joint and muscular pain and depression, have been reported several months after Chikungunya virus (CHIKV) infection. Their frequency and their impact on quality of life have not been compared with those of an unexposed population. In the present study, we aimed to describe the frequency of prolonged clinical manifestations of CHIKV infection and to measure the impact on quality of life and health care consumption in comparison with that of an unexposed population, more than one year after infection.
View Article and Find Full Text PDF