Publications by authors named "Mamuka Bokuchava"
Article Synopsis
- * A systematic review of studies on veno-active drugs (VADs) revealed that only specific treatments like micronized purified flavonoid fraction (MPFF), aminaphthone, and low-dose diosmin showed statistically significant improvements in HRQoL compared to placebo.
- * The research included data from various sources, highlighting a discrepancy between patient and physician perceptions regarding the impact of CVD, where physicians often underestimate the emotional and physical toll on patients.
Background: This study aimed to assess the efficacy and safety of Actovegin for the treatment of patients with Fontaine stage IIB peripheral arterial disease (PAD).
Methods: The study included 366 patients with Fontaine stage IIB PAD from 19 centers (Russia, Georgia, Kazakhstan). Placebo or Actovegin (1200 mg daily [QD]) were administered intravenously for two weeks, followed by a 10-week course of oral administration (placebo or Actovegin 1200 mg QD).