Publications by authors named "Mamu Shimizu"
Article Synopsis
- Impaired renal function is a significant negative factor in dogs with myxomatous mitral valve disease (MMVD), and the study investigates the role of cystatin C (Cys-C) as a prognostic marker for this condition.
- Fifty small-breed dogs with MMVD were analyzed to determine the association between serum Cys-C levels and MMVD-related mortality using Cox regression and survival curve analysis.
- Results indicated that higher Cys-C concentrations correlate with a significantly shorter survival time and worse prognosis for MMVD, even in dogs with normal creatinine levels.
Periodontal disease (PD) is the most common oral disease that is caused by infection with periodontal-disease-associated bacteria (PDAB) such as and in dogs as well as in humans. Unlike humans, most dogs do not follow daily oral hygiene routine, and this results in many dogs being affected by PD. Thus, to prevent PD, it is important to control PDAB.
View Article and Find Full Text PDFThis study investigated the effects of age, sex and breed on serum cystatin C (Cys-C) and creatinine in small breed dogs. This retrospective study included 250 dogs weighing less than 15 kg without azotemia. Serum Cys-C and creatinine concentrations were analyzed, along with their correlation with age, and the difference between sexes or dog breeds.
View Article and Find Full Text PDFThe standard procedure to treat oronasal fistula in dogs requires tooth extraction to close the fistula; hence, the subject would lose its tooth. In this study, trafermin was applied to four dog models with oronasal fistula to investigate the periodontal tissue regenerative effects of trafermin in the treatment without tooth extraction. A fistula was created along the palatal side of each upper canine tooth.
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