Publications by authors named "Mamta Patel Nagaraja"
Article Synopsis
- Osteoporosis and disuse-induced bone loss affect millions in the U.S., while astronauts face similar challenges in microgravity, leading to concerns about bone health during space missions.
- Current treatments slow osteoporosis progression, and there are promising strategies emerging to combat bone loss in astronauts, including high impact activities like running and low magnitude mechanical loading.
- Despite clinical trials showing low magnitude, high frequency loading can help normalize bone loss, the specific tissues and mechanisms involved in this response are still not fully understood.
Article Synopsis
- Bone loss is a significant issue for astronauts during spaceflights, as it can occur both in short and long durations, and it can be studied on Earth through various models.
- Scientists use in vitro simulators like clinostats and in vivo methods such as bed rest studies to mimic the effects of microgravity and understand the underlying pathology.
- Despite extensive research, current countermeasures have not been very successful in preventing bone loss, highlighting the need for ongoing studies and new strategies to address this concern.
