Publications by authors named "Mamiko Hoshi"

Background: Tocilizumab is effective in treating severe coronavirus disease 2019 (COVID-19). However, the specific time point it acts as a valid indicator of treatment efficacy remains unclear. This study aimed to determine the optimal day for assessing the prognostic value of the oxygen saturation/fraction of inspired oxygen (SpO/FiO) and ratio of respiratory rate-oxygenation (ROX) index in patients receiving tocilizumab for COVID-19.

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Article Synopsis
  • * A study analyzed 97 OSAS patients and categorized them into clusters based on their clinical features and leptin levels, observing that some had normal levels while others had high levels despite similar obesity.
  • * After 6 months of CPAP treatment, excessive daytime sleepiness improved across all clusters, and leptin levels decreased significantly in one group; however, the role of leptin as a biomarker for CPAP efficacy remains inconclusive.
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A 54-year-old man whose awake percutaneous arterial oxygen saturation (SpO) was 94% was diagnosed with obstructive sleep apnea by polysomnography (PSG). His apnea-hypopnea index (AHI) was 138.8 (AI: 4.

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A woman in her late 20s who had received an implantable cardioverter defibrillator in childhood for ventricular arrhythmia was diagnosed with severe obstructive sleep apnoea (apnoea-hypopnoea index, 77.1/h), and she began continuous positive airway pressure treatment. Before initiating this treatment, she had moderate hypoxaemia of unknown cause.

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