[Effect of visual cortex stimulation on lipid peroxidation in the rabbit retina].

Chronic experiments on rabbits have shown that visual cortex stimulation resulted in intensified lipid peroxidation in the retina with the parallel decrease of electroretinogram amplitude parameters. The transsection of the optic nerve resulting in the elimination of retinal corticofugal inputs diminished the accumulation of lipid peroxidation products in the rabbit retina during light adaptation. Preliminary insertion of antioxidants to animals (vitamin E and ionol) prevents the inhibitory effect of the cortex on the function of the retina.

[Phylo- and ontogenic characteristics of lipid peroxidation in the retina of vertebrates].

Phylo- and ontogenetic aspects of lipid peroxidation and antioxidative enzyme system in the retina of vertebrates were studied. It was established that both the intensity of lipid peroxidation and the activity of glutathione peroxidase in the retina of different vertebrate animals (carp, frog, tortoise, pigeon, rabbit) considerably diminished with evolution. The differences in the intensity of lipid peroxidation and the activity of glutathione peroxidase between dark- and light-adapted retinas also decreased depending on the level of the development.