Publications by authors named "Mamdouh Fahmy El-Mekawy"
Seroprevalence and risk factors of infectious bovine rhinotracheitis in cattle in Gharbia governorate, Egypt: A comparative study of traditional and commercial production systems.
Mostafa El-Sayed El-Sheikh Lotfy Bakar Mamdouh Fahmy El-Mekawy Mohammed Ibrahim Eisa Nasser Zeidan Abouzeid
Open Vet J
November 2024
Background: Infectious bovine rhinotracheitis (IBR) is a global contagious respiratory disease of ruminants caused by Bovine Herpes virus-1 (BoHV-1). It causes substantial financial losses in the dairy industry worldwide and is considered one of the most important causative agents of abortion and reproductive problems in dairy cattle.
Aim: This study aimed to estimate the seroprevalence of IBR and the related risk factors in the dairy population in Gharbia governorate, Egypt.
Article Synopsis
- - The study investigates the immune response triggered by two types of vaccines—an inactivated vaccine (CATTLEWIN-5K) and a modified live vaccine (MLV, Cattle Master Gold FP)—against bovine respiratory disease (BRD) in seronegative heifers.
- - Twenty heifers were divided into three groups: a control group (no vaccination) and two vaccinated groups receiving either the MLV or inactivated vaccine. The immune response was measured by analyzing the expression of interleukin-6 (IL-6) and interferon-gamma (INF-γ) at various days post-vaccination.
- - Results showed that both vaccines upregulated IL-6 and INF-γ levels, with