Publications by authors named "Mamatchi Melila"

oil, a substance with a rich history of use for its nutritional, therapeutic, traditional, and cosmetic benefits, was the focus of our study. We investigated the impact of consuming edible oil from . arils on Wistar rats.

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Togo's phosphate processing plant at Kpeme discharges waste, containing Cd, Pb, and fluoride, into the sea and on the soil. Heavy metals toxicity on kidneys and the liver has been studied. However, fluoride toxicity on these organs remains to be investigated.

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The biomedical analysis laboratory is a structure intended to carry out biological, immuno-serological, biochemical, hematological or other examinations of substances of human origin to provide information useful for the diagnosis, management, prevention or treatment of diseases. These laboratories produce solid and liquid biomedical waste (BMW) that constitutes a serious health problem for humans and their environment. Temain goal of this study is to assess the management of solid BMW produced by biomedical laboratories in Togo.

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Article Synopsis
  • Combretum micranthum (CM) is a plant widely used in West African traditional medicine for treating various health issues, including kidney disorders.
  • The study aims to investigate the protective effects of a standardized CM extract on kidney damage caused by diabetes in rats and to analyze its bioactive compounds through computational methods.
  • Methodology involved inducing diabetes in rats, treating them with CM extract, and conducting various biochemical tests over eight weeks to assess kidney function and damage.*
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Article Synopsis
  • The study focuses on the toxicity profile of the hydroalcoholic extract from the leaves of Combretum micranthum (CM), which is traditionally used for treating various ailments in West Africa.
  • Researchers conducted acute and sub-chronic toxicity tests on rats to assess potential toxic effects, including behavioral changes and organ health.
  • Results showed no signs of toxicity or adverse effects at high doses, indicating that CM extract may not contain harmful compounds, specifically cyanide, based on Fourier transform infrared spectrophotometry.
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In Togo, the phosphate ore mill discharges waste containing xenobiotics like cadmium, lead and fluoride. If the role of heavy metals in the appearance of pathologies is known, the role of fluoride remains to be studied alongside xenobiotics. This study tested the hypothesis that the toxicity of fluoride contributes, along with heavy metals, to physiological dysfunction.

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