Influence of Neighborhood Socioeconomic Deprivation on Effectiveness of an Intensive Lifestyle Intervention.

Objective: To assess the influence of neighborhood socioeconomic deprivation on the effectiveness of an intensive lifestyle intervention (ILI) in the Look AHEAD trial.

Research Design And Methods: Look AHEAD randomized adults with overweight/obesity and type 2 diabetes to ILI for weight loss, or Diabetes Support and Education (DSE). We linked participant data from four study sites to the 2000 United States Census to generate a neighborhood socioeconomic deprivation score.

Observer design for a schistosomiasis model.

This paper deals with the state estimation for a schistosomiasis infection dynamical model described by a continuous nonlinear system when only the infected human population is measured. The central idea is studied following two major angles. On the one hand, when all the parameters of the model are supposed to be well known, we construct a simple observer and a high-gain Luenberger observer based on a canonical controller form and conceived for the nonlinear dynamics where it is implemented.